Team:LMU-Munich/Laboratory Safety

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==Lab and Project Safety==
 
Here you find our considerations on the following topics of biological safety for our project:  
Here you find our considerations on the following topics of biological safety for our project:  
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The other subproject, [[Team:LMU-Munich/Spore_Coat_Proteins|'''Sporo'''bead]] involves the creation of GMOs which have unknown effects to the public or the environment. Although we have great plans for the use of our Sporo'''beads''', they never leave our laboratory, so they cannot harm the public or environment. For possible future applications, we will prevent the germination of our '''Sporo'''beads in two different ways ([[Team:LMU-Munich/Germination_Stop|'''Germination'''Stop]]), so that they cannot proliferate. This is our approach towards the safety of our Sporo'''beads'''.
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The other subproject, [[Team:LMU-Munich/Spore_Coat_Proteins|'''Sporo'''bead]] involves the creation of GMOs which have unknown effects to the public or the environment. Although we have great plans for the use of our '''Sporo'''beads, they never leave our laboratory, so they cannot harm the public or environment. For possible future applications, we will prevent the germination of our '''Sporo'''beads in two different ways ([[Team:LMU-Munich/Germination_Stop|'''Germination'''Stop]]), so that they cannot proliferate. This is our approach towards the safety of our '''Sporo'''beads.
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We have not worked on it yet, but there also is the possibility to remove antibiotic resitance genes from the ''Bacillus subtilis'' genome (for example with [https://static.igem.org/mediawiki/2012/6/6d/LMU-Munich_2012_Clean_deletions_in_Bacillus_subtilis.pdf pMAD], a vector that we used to delete genes in ''B. subtilis''). All of our constructs are used while being integrated into the genome. Therefore all resistances could be removed (without removing the functional constructs) before the use of the Sporo'''beads'''. Other pathogens would thereby not have the possibility to grab resistance genes from our strains.
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We have not worked on it yet, but there also is the possibility to remove antibiotic resitance genes from the ''Bacillus subtilis'' genome (for example with [https://static.igem.org/mediawiki/2012/6/6d/LMU-Munich_2012_Clean_deletions_in_Bacillus_subtilis.pdf pMAD], a vector that we used to delete genes in ''B. subtilis''). All of our constructs are used while being integrated into the genome. Therefore all resistances could be removed (without removing the functional constructs) before the use of the '''Sporo'''beads. Other pathogens would thereby not have the possibility to grab resistance genes from our strains.
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Latest revision as of 14:15, 26 October 2012

iGEM Ludwig-Maximilians-Universität München Beadzillus

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The LMU-Munich team is exuberantly happy about the great success at the World Championship Jamboree in Boston. Our project Beadzillus finished 4th and won the prize for the "Best Wiki" (with Slovenia) and "Best New Application Project".

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