Team:Evry

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<title>Welcome ot iGEM Evry's Wiki!</title>
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<h1>Welcome to our French Froggies project</h1>
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<em>We are working on this wiki along with the advancement of our project, so come again soon to see the project and the wiki evolving!</em>
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<h2>Project</h2>
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Building on a long-standing French fascination for frogs, we wanted to spread this enthusiasm to the world of synthetic biology by introducing a new, vertebrate chassis to the community: Xenopus tropicalis. This leap towards multicellular biological engineering required new tools, so we first developed a new set of frog compatible vectors, biobricked tissue specific promoters and a new technique to assemble them in a single shot. To benefit from tissue compartmentalisation, we created a synthetic, orthogonal hormonal system using the plant molecule auxin. We also investigated E. coli/Xenopus interfacing, effectively creating a synthetic ecosystem. We modelled our system at the organism scale, using a multi-level and multi-technique approach. Finally, working with whole animals during iGEM brought a load of difficult ethical questions regarding animal biotechnologies and experimentation. This led us to wonder: Are we a chassis?
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<h1 align="center">Welcome to the French Froggies Home Page!</h1>
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<p> Visit our <a href="https://2012.igem.org/Team:Evry/Project">project</a> to understand deeper what we are working on. </p>
 
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<h2>Composition of our team</h2>
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<p>This year, the Evry iGEM team is bringing synthetic biology to multicellular organisms, opening the era of <em>synthetic physiology</em>. We created the <a href="https://2012.igem.org/Team:Evry/FrenchFrog"><em>first parts for Xenopus</em></a> and an <a href="https://2012.igem.org/Team:Evry/AIDSystem"><em>synthetic orthogonal hormonal</em></a> system to link them together. We also created new tools for <a href="https://2012.igem.org/Team:Evry/Modeling"><em>modeling the tadpole</em></a> physiology, <a href="https://2012.igem.org/Team:Evry/GB"><em>assemble multiple parts</em></a> in a single shot, wrote a <a href="https://2012.igem.org/Team:Evry/FrogForDummies"><em>guidebook</em></a> to help future teams with <i>Xenopus</i> and studied the <a href="https://2012.igem.org/Team:Evry/HumanPractice/Introduction"><em>consequences of the arrival</em></a> of vertebrates in iGEM.</p>
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<p>You can have a look at our <a href="https://2012.igem.org/Team:Evry/Achievements"><em>achievements page</em></a> or visit the universe of multicellular synthetic biology by clicking on the galaxy below !</p>
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<p>The composition of our team is available.<a href="https://2012.igem.org/Team:Evry/Team"> Click here to visit our team page</a></p>
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<h2>Acheivements</h2>
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<p>This is the list of the acheivement of our team working. Click on the elements of the list to get to the page:</p>
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<li>We have created the first biobrick parts to work in Xenopus Tropicalis, and most of our new parts have enhanced expression in mammalian and other vertebrates cells</li>
 
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<li>We have developped a new methodology to model the physiology of a vertebrate at the organism scale</li>
 
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<li>We have been explorating the ethical and social impact of engineering living animals</li>
 
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<li>... To be completed</li>
 
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Latest revision as of 03:47, 27 October 2012

Welcome ot iGEM Evry's Wiki!

Welcome to the French Froggies Home Page!

This year, the Evry iGEM team is bringing synthetic biology to multicellular organisms, opening the era of synthetic physiology. We created the first parts for Xenopus and an synthetic orthogonal hormonal system to link them together. We also created new tools for modeling the tadpole physiology, assemble multiple parts in a single shot, wrote a guidebook to help future teams with Xenopus and studied the consequences of the arrival of vertebrates in iGEM.

You can have a look at our achievements page or visit the universe of multicellular synthetic biology by clicking on the galaxy below !

Retrieved from "http://2012.igem.org/Team:Evry"