Team:NTNU Trondheim/Equations

From 2012.igem.org

(Difference between revisions)
Line 38: Line 38:
|Lldr2Lact -> Lldr
|Lldr2Lact -> Lldr
|0.0001
|0.0001
-
|Degradation of Lldr-Lactate complex
+
|Degradation of Lldr in Lldr-Lactate complex
|-
|-
|Lldr2 + pLact -> pLactLldr2
|Lldr2 + pLact -> pLactLldr2
Line 47: Line 47:
|0.1
|0.1
|Unbinding of dimer to promoter
|Unbinding of dimer to promoter
 +
|-
 +
|pLactLldr2 -> Lldr + pLact
 +
|0.0001
 +
|Degradation of Lldr bound to prooter.
 +
|-
 +
|pLactLldr2 + Lact -> pLactLldr2Lact + Lact
 +
|0.0001
 +
|Binding of lactate to promoter dimer complex.
 +
|-
 +
|pLactLldr2Lact -> pLactLldr2
 +
|1
 +
|Release of lactate from promoter dimer complex.
 +
|-
|}
|}

Revision as of 09:45, 13 August 2012

Search and Destroy
Search and Destroy
NTNU IS B.A.C.K.
Bacterial Anti-Cancer-Kamikaze

Model equations
Reaction Propensity Comments
ø -> Lldr 0.1 Constant production of Lldr
Lldr -> ø 0.0001 Constant degradation of Lldr relative to the creation of Lldr giving a molecule number of 1000.
2 Lldr -> Lldr2 3 Dimerization of Lldr
Lldr2 -> 2 Lldr 100 Undimerization of Lldr giving a majority of Lldr in dimer.
Lldr2 -> Lldr 0.0001 Degradation of Lldr dimer.
Lldr2 + Lact -> Lldr2Lact 0.0001 Binding of lactate to Lldr dimer. Lactate is notconsumed.
Lldr2Lact -> Lldr2 1 Unbinding of Lactate to dimer
Lldr2Lact -> Lldr 0.0001 Degradation of Lldr in Lldr-Lactate complex
Lldr2 + pLact -> pLactLldr2 1 Binding of dimer to lld promoter
pLactLldr2 -> Lldr2 + pLact 0.1 Unbinding of dimer to promoter
pLactLldr2 -> Lldr + pLact 0.0001 Degradation of Lldr bound to prooter.
pLactLldr2 + Lact -> pLactLldr2Lact + Lact 0.0001 Binding of lactate to promoter dimer complex.
pLactLldr2Lact -> pLactLldr2 1 Release of lactate from promoter dimer complex.
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