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Team:Lyon-INSA/results
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| - | + | Every year industries spend billions of dollars to get rid of the biofilms which develop in their installations. Indeed biofims are reponsible for :<br/><br/> | |
| + | <li>Food spoilage or poisoning in the food industry<br/> | ||
| + | <li>Pathogens' persistence and dispersal in health industry<br/> | ||
| + | <li>Corrosion and diameter reduction of pipelines<br/><br/> | ||
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| + | At the moment, industries have some solutions at their disposal to limit the biofilm development but they have generaly an environmental impact and/or an important cost.<br/><br/> | ||
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| + | Thus, we develop a new generation of solution against biofilms in industry, which allows to reduce : <br/><br/> | ||
| - | + | <li>The use of harmful chemical reagents in cleaning processes<br/> | |
| - | + | <li>The cleaning costs for industrialists<br/> | |
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| - | <br> | + | <br/> |
| - | + | Our solution is based on engineered bacterial "torpedos" capable of infiltrating, destroying biofilms (<strong>KILL</strong>) and protecting the cleaned surfaces by either a surfactant coating (<strong>COAT</strong> option), or by establishment of a positive biofilm (<strong> STICK </strong> option).<br/> | |
| - | or by establishment of a positive biofilm (<strong> STICK </strong> option).<br/> | + | |
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<center><img src="https://static.igem.org/mediawiki/2012/c/cb/ModelBs.jpg" width = 450px/></center><br/> | <center><img src="https://static.igem.org/mediawiki/2012/c/cb/ModelBs.jpg" width = 450px/></center><br/> | ||
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| - | < | + | This tunneling activity of <i>Bacillus subtilis</i> swimmer cells enables to : |
| - | + | <li>Facilitate the delivery of the active substances within the biofilm.</li> | |
| - | < | + | <li>Destroy the inacessible biofilms in pipes.</li><br/> |
| - | <li> | + | |
| - | + | Moreover <i>Bacillus</i> strains are non pathogenic and do not cause equipment deteroriation by corrosion. | |
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| - | + | To sum up, this biocide-alternative strategy provides a money-saving and an environementally friendly solution for the control of unwanted biofilm.<br/><br/> | |
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| - | <strong> LYSOSTAPHIN</strong> part <a href="http://partsregistry.org/wiki/index.php?title=Part:BBa_K802000" target="_blank"><font color="#664499"><b> | + | <strong> LYSOSTAPHIN</strong> part <a href="http://partsregistry.org/wiki/index.php?title=Part:BBa_K802000" target="_blank"><font color="#664499"><b> BBa_K802000</b></font></a> <br/><br/> |
<center><img src="https://static.igem.org/mediawiki/2012/f/f3/Lyso.jpg" width = 650px/></center><br/> | <center><img src="https://static.igem.org/mediawiki/2012/f/f3/Lyso.jpg" width = 650px/></center><br/> | ||
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<center><img src="https://static.igem.org/mediawiki/2012/4/44/Lysostaphin.jpg" width = 650px/></center><br/> | <center><img src="https://static.igem.org/mediawiki/2012/4/44/Lysostaphin.jpg" width = 650px/></center><br/> | ||
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| - | <strong> DISPERSIN</strong> part BBa_K802001<br/><br/> | + | <strong> DISPERSIN</strong> part <a href="http://partsregistry.org/wiki/index.php?title=Part:BBa_K802001" target="_blank"><font color="#664499"><b> BBa_K802001</b></font></a> <br/><br/> |
<center><img src="https://static.igem.org/mediawiki/2012/e/e9/Dispersin.jpg" width = 650px/></center><br/><br/> | <center><img src="https://static.igem.org/mediawiki/2012/e/e9/Dispersin.jpg" width = 650px/></center><br/><br/> | ||
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| - | <strong> SURFACTIN + BIOFILM</strong> part BBa_K802009<br/><br/> | + | <strong> SURFACTIN + BIOFILM</strong> part <a href="http://partsregistry.org/wiki/index.php?title=Part:BBa_K802009" target="_blank"><font color="#664499"><b> BBa_K802009</b></font></a><br/><br/> |
<center><img src="https://static.igem.org/mediawiki/2012/3/31/Coatstick.jpg" width = 650px/></center><br/> | <center><img src="https://static.igem.org/mediawiki/2012/3/31/Coatstick.jpg" width = 650px/></center><br/> | ||
Latest revision as of 21:31, 26 October 2012
Context and Objectives
Every year industries spend billions of dollars to get rid of the biofilms which develop in their installations. Indeed biofims are reponsible for :
At the moment, industries have some solutions at their disposal to limit the biofilm development but they have generaly an environmental impact and/or an important cost.
Thus, we develop a new generation of solution against biofilms in industry, which allows to reduce :
PROJECT STRATEGY
Our solution is based on engineered bacterial "torpedos" capable of infiltrating, destroying biofilms (KILL) and protecting the cleaned surfaces by either a surfactant coating (COAT option), or by establishment of a positive biofilm ( STICK option).
This tunneling activity of Bacillus subtilis swimmer cells enables to :
Moreover Bacillus strains are non pathogenic and do not cause equipment deteroriation by corrosion.
To sum up, this biocide-alternative strategy provides a money-saving and an environementally friendly solution for the control of unwanted biofilm.
