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| | <center><h2>Introduction</h2></center> | | <center><h2>Introduction</h2></center> |
| - | The Dundee iGem team began this project with a series of meetings during which ideas were explored, and areas of interest were discussed to find a project focus that appealed to the team. After much debating, the area of healthcare was chosen, and the project goals were refined to concentrate on a method to counteract corruption of the natural gut flora balance by clostridium difficile (<em>C.Diff</em>). Individuals undergoing long term antibiotic treatment can suffer from pseudomembranous colitis caused by <em>C.Diff</em>, and the team's aim is to modify Escherichia coli (<em>E.Coli</em>) to attack <em>C.Diff </em> in a manner that restores the natural balance of the gut flora. | + | The Dundee iGem team began this project with a series of meetings during which ideas were explored, and areas of interest were discussed to find a project focus that appealed to the team. After much debating, the area of healthcare was chosen, and the project goals were refined to concentrate on a method to counteract corruption of the natural gut flora balance by clostridium difficile (<em>C. diff.</em>). Individuals undergoing long term antibiotic treatment can suffer from pseudomembranous colitis caused by <em>C. diff.</em>, and the team's aim is to modify Escherichia coli (<em>E. coli</em>) to attack <em>C. diff. </em> in a manner that restores the natural balance of the gut flora. |
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| | <div class="box green small left"> | | <div class="box green small left"> |
| - | <center><h2>Heading</h2></center> | + | <center><h2><em>C.Diff</em> Lysis</h2></center> |
| - | Lorem ipsum dolor sit amet, consectetur adipiscing elit. Vivamus sapien ante, suscipit vitae fringilla a, pulvinar ut augue. Cum sociis natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Praesent mattis justo vel elit mattis vitae sodales elit sagittis. Praesent sagittis ornare justo, quis rhoncus odio sollicitudin ac. Mauris varius lorem in sapien tristique mattis. Etiam tristique adipiscing ipsum, ut imperdiet nulla elementum pharetra. Nulla lorem mi, posuere quis faucibus id, tempus ut risus. Duis ut velit sem. | + | Recent research [] investigating <em>C. diff.</em> cell disruption presents evidence that bacteriophage ΦCD27 encodes an endolysin that can be expressed within <em>E.coli</em>. |
| | </div> | | </div> |
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Introduction
The Dundee iGem team began this project with a series of meetings during which ideas were explored, and areas of interest were discussed to find a project focus that appealed to the team. After much debating, the area of healthcare was chosen, and the project goals were refined to concentrate on a method to counteract corruption of the natural gut flora balance by clostridium difficile (C. diff.). Individuals undergoing long term antibiotic treatment can suffer from pseudomembranous colitis caused by C. diff., and the team's aim is to modify Escherichia coli (E. coli) to attack C. diff. in a manner that restores the natural balance of the gut flora.
C.Diff Lysis
Recent research [] investigating C. diff. cell disruption presents evidence that bacteriophage ΦCD27 encodes an endolysin that can be expressed within E.coli.
Heading
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Vivamus sapien ante, suscipit vitae fringilla a, pulvinar ut augue. Cum sociis natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Praesent mattis justo vel elit mattis vitae sodales elit sagittis. Praesent sagittis ornare justo, quis rhoncus odio sollicitudin ac. Mauris varius lorem in sapien tristique mattis. Etiam tristique adipiscing ipsum, ut imperdiet nulla elementum pharetra. Nulla lorem mi, posuere quis faucibus id, tempus ut risus. Duis ut velit sem.
Accomplishments
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