Team:Trieste

From 2012.igem.org

(Difference between revisions)
(fix layout)
 
(3 intermediate revisions not shown)
Line 12: Line 12:
<h2>We present you the Jolly JoCare</h2>
<h2>We present you the Jolly JoCare</h2>
<iframe width="330" height="280" src="http://www.youtube.com/embed/vB5xmbLnj7I" frameborder="0" allowfullscreen></iframe>
<iframe width="330" height="280" src="http://www.youtube.com/embed/vB5xmbLnj7I" frameborder="0" allowfullscreen></iframe>
-
<br/>
 
<p>
<p>
-
<a href="https://2012.igem.org/Team:Trieste/project/overview"target="_blank">Project Overview</a>
+
<a href="https://2012.igem.org/Team:Trieste/project/overview" target="_blank">Project Overview</a>
- Have a look to our Jolly JoCare Project at a glance!
- Have a look to our Jolly JoCare Project at a glance!
</p>
</p>
<p>
<p>
-
<h2></h2>
+
<strong> Abstract </strong> <br/>
-
<strong> Absrtact </strong> <br/>
+
Recent studies have evidenced that having a beneficial and healthy intestinal microflora is very important for human health. Our aim is to modify a bacteria normally found in human gut and create a safe, controllable and versatile molecular platform which can be used to produce a wide range of molecules  leading to a beneficial probiotic. For this purpose we have chosen the <i>E. coli</i> strain Nissle 1917 which has been used for many years as a probiotic. We designed a robust gene guard system regulated by a novel and easy to control inducible cumate switch that activates the production of a human antimicrobial peptide LL-37 that can kill the bacteria and also avoid horizontal transfer.   
Recent studies have evidenced that having a beneficial and healthy intestinal microflora is very important for human health. Our aim is to modify a bacteria normally found in human gut and create a safe, controllable and versatile molecular platform which can be used to produce a wide range of molecules  leading to a beneficial probiotic. For this purpose we have chosen the <i>E. coli</i> strain Nissle 1917 which has been used for many years as a probiotic. We designed a robust gene guard system regulated by a novel and easy to control inducible cumate switch that activates the production of a human antimicrobial peptide LL-37 that can kill the bacteria and also avoid horizontal transfer.   
The safe probiotic constructed here can be used to produce nutritious, preventive or therapeutic molecules. For example, we have used it to produce an antibody against the emerging virus, Norovirus.  
The safe probiotic constructed here can be used to produce nutritious, preventive or therapeutic molecules. For example, we have used it to produce an antibody against the emerging virus, Norovirus.  
-
</p>
+
</p>                                   
-
<br/>  <br/>                                   
+
</div> <!-- end box_left -->
</div> <!-- end box_left -->
<div id="box_main"> <!-- start box_main -->
<div id="box_main"> <!-- start box_main -->
Line 60: Line 57:
<div class="read_more"><a href="https://2012.igem.org/Team:Trieste/data"target="_blank">a</a></div>
<div class="read_more"><a href="https://2012.igem.org/Team:Trieste/data"target="_blank">a</a></div>
</div>
</div>
-
<h2></h2>
+
<br/>
-
<br/>
+
<img src="https://static.igem.org/mediawiki/2012/6/64/Foto_home_cumato_tag.jpg"alt="#" width="300px"/>
-
<td><img src="https://static.igem.org/mediawiki/2012/6/64/Foto_home_cumato_tag.jpg"alt="#" width="300px"/>
+
</div> <!-- end box-article -->
-
<br/> <br/> </div> <!-- end box-article -->
+
</div>
</div>
</div> <!-- end box_main -->
</div> <!-- end box_main -->
Line 70: Line 66:
</ul>
</ul>
<img src="https://static.igem.org/mediawiki/2012/b/b0/Team_trieste.jpg" alt="Team iGEM 2012" id="igem_team" />
<img src="https://static.igem.org/mediawiki/2012/b/b0/Team_trieste.jpg" alt="Team iGEM 2012" id="igem_team" />
-
<br/>
+
<br/>
<div class="box_contacts">
<div class="box_contacts">
Line 79: Line 75:
Follow us also:
Follow us also:
<a href="https://www.facebook.com/IGEMUNITS?ref=ts" target="_blank"><img src="https://static.igem.org/mediawiki/2012/f/f4/Ico_fb.png" alt="Facebook" class="fb" /></a>
<a href="https://www.facebook.com/IGEMUNITS?ref=ts" target="_blank"><img src="https://static.igem.org/mediawiki/2012/f/f4/Ico_fb.png" alt="Facebook" class="fb" /></a>
-
<a href="https://twitter.com/igemunits" target="_blank"><img src="https://static.igem.org/mediawiki/2012/2/21/Ico_twitter.png" alt="twitter" class="tw" /></a>
+
<a href="https://twitter.com/iGEMTrieste" target="_blank"><img src="https://static.igem.org/mediawiki/2012/2/21/Ico_twitter.png" alt="twitter" class="tw" /></a>
</div>
</div>
</div>
</div>
-
<br/> <br/><br/>
+
<br/> <br/><br/>
-
<img src="https://static.igem.org/mediawiki/2012/9/9c/TriesteIMG_3711_copia.jpg" alt="sec photo team trieste" width="230px"/>
+
<img src="https://static.igem.org/mediawiki/2012/7/70/Trieste_foto_home_2.jpg" alt="sec photo team trieste" width="230px" height="140" />
</div> <!-- end box_right -->
</div> <!-- end box_right -->

Latest revision as of 02:10, 27 September 2012

Our Project

Quick Links

The Team

We present you the Jolly JoCare

Project Overview - Have a look to our Jolly JoCare Project at a glance!

Abstract
Recent studies have evidenced that having a beneficial and healthy intestinal microflora is very important for human health. Our aim is to modify a bacteria normally found in human gut and create a safe, controllable and versatile molecular platform which can be used to produce a wide range of molecules leading to a beneficial probiotic. For this purpose we have chosen the E. coli strain Nissle 1917 which has been used for many years as a probiotic. We designed a robust gene guard system regulated by a novel and easy to control inducible cumate switch that activates the production of a human antimicrobial peptide LL-37 that can kill the bacteria and also avoid horizontal transfer. The safe probiotic constructed here can be used to produce nutritious, preventive or therapeutic molecules. For example, we have used it to produce an antibody against the emerging virus, Norovirus.

Achievements
Quick link to our judging form and Achievements summary
a
Main Results
Click here to reach our summary page.
a
Data
Here are our favourite parts!


#
Team iGEM 2012

Contact us

For other information, write to:

igem2012@gmail.com



sec photo team trieste
Università degli studi di Trieste ICGEB Illy Fondazione Cassa di Risparmio
iGEM 2012 iGEM 2012 iGEM 2012 iGEM 2012 iGEM 2012 iGEM 2012
HTML Hit Counter