Team:Bonn

From 2012.igem.org

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'''This page is currently under construction.  
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{{Template:Team:Bonn}}
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__NOTOC__
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<!--- The Mission, Experiments --->
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{| style="color:#5e92d2;background-color:#ffffff;" cellpadding="5" cellspacing="1" border="0" bordercolor="#fff" width="100%" align="left"
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!align="center"|[[Team:Bonn|<span style="color:#005186;">Home]]
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!align="center"|[[Team:Bonn/Team|<span style="color:#4f8dde;">Team]]
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!align="center"|[[Team:Bonn/Project|<span style="color:#4f8dde;">Project]]
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!align="center"|[[Team:Bonn/Activities|<span style="color:#4f8dde;">Other Activities]]
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!align="center"|[[Team:Bonn/Parts|<span style="color:#4f8dde;">Parts Submitted to the Registry]]
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!align="center"|[[Team:Bonn/Notebook|<span style="color:#4f8dde;">Notebook]]
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!align="center"|[[Team:Bonn/Safety|<span style="color:#4f8dde;">Safety]]
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!align="center"|[[Team:Bonn/Attributions|<span style="color:#4f8dde;">Attributions]]
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!align="center"|[[Team:Bonn/Sponsors|<span style="color:#4f8dde;">Sponsors]]
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|}
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{|align="center"
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|[[Image:dna-separation-bar.png|960px|no frame|link=]]
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|}
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'''To visit our website at University of Bonn click [http://igem12.uni-bonn.de/en/ HERE].'''
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<div style="float:right;">
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[[Image:Bonn_lovlogo.png|200px]]
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<br/><br/><br/><br/>
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[[Image:Bonn_team.png|thumb|iGEM Team Bonn 2012]]
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</div>
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{|align="justify"
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Fusion protein design has always been time- and design-intensive, to say the least.
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|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
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We are developing and characterizing a fusion construct containing a light sensitive domain,
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|[[Image:Bonn_logo.png|200px|right|frame]]
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providing easy coupling and light activation of proteins of interest to investigators, thus
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developing a system to modify protein activity on protein-level just by using blue light.
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''Tell us more about your project. Give us background.  Use this as the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
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|[[Image:Bonn_team.png|right|frame|Your team picture]]
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|align="center"|[[Team:Bonn | Team Bonn]]
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|}
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<!--- The Mission, Experiments --->
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Using the LOV (Light, Oxygen, Voltage) domain commonly found in plants, where it enables light-directed growth, we are establishing guidelines for coupling many interesting proteins to the LOV domain, which allows control of protein activity through blue wavelength light.
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{| style="color:#1b2c8a;background-color:#5E92D2;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
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Designing our activity modifying structure at protein level allows quick response times (2.2 microseconds activation time, 85 seconds de-
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!align="center"|[[Team:Bonn|Home]]
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activation time). A device of that kind could be of great importance as a tool for disinfection on a laboratory scale or mutant selection via blue light. Further potential applications of our LOV fusion system might include bioreactor regulation or site-specific drug activation.
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!align="center"|[[Team:Bonn/Team|Team]]
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!align="center"|[https://igem.org/Team.cgi?year=2012&team_name=Bonn Official Team Profile]
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!align="center"|[[Team:Bonn/Project|Project]]
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!align="center"|[[Team:Bonn/Parts|Parts Submitted to the Registry]]
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'''To visit our website at University of Bonn click [http://igem12.uni-bonn.de/en/ HERE].'''
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!align="center"|[[Team:Bonn/Modeling|Modeling]]
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!align="center"|[[Team:Bonn/Notebook|Notebook]]
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!align="center"|[[Team:Bonn/Safety|Safety]]
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!align="center"|[[Team:Bonn/Attributions|Attributions]]
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!align="center"|[[Team:Bonn/Sponsors|Sponsors]]
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|}
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Latest revision as of 00:30, 27 September 2012

iGEM Team Bonn Header

Home Team Project Other Activities Parts Submitted to the Registry Notebook Safety Attributions Sponsors
no frame

Bonn lovlogo.png



iGEM Team Bonn 2012


Fusion protein design has always been time- and design-intensive, to say the least. We are developing and characterizing a fusion construct containing a light sensitive domain, providing easy coupling and light activation of proteins of interest to investigators, thus developing a system to modify protein activity on protein-level just by using blue light.

Using the LOV (Light, Oxygen, Voltage) domain commonly found in plants, where it enables light-directed growth, we are establishing guidelines for coupling many interesting proteins to the LOV domain, which allows control of protein activity through blue wavelength light.

Designing our activity modifying structure at protein level allows quick response times (2.2 microseconds activation time, 85 seconds de- activation time). A device of that kind could be of great importance as a tool for disinfection on a laboratory scale or mutant selection via blue light. Further potential applications of our LOV fusion system might include bioreactor regulation or site-specific drug activation.


To visit our website at University of Bonn click [http://igem12.uni-bonn.de/en/ HERE].

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