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      <p><em>Rhodopseudomonas palustris</em> has an extraordinary metabolic versatility; this organism can grow in a wide variety of environmental conditions. <em>R palustris</em> obtain energy by different  mechanism including <strong>anoxygenic</strong> <strong>photosynthesis, aerobic and anaerobic  respiration</strong>. </p>
 
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      <p>&nbsp;</p>
 
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      <p><img src="images/Cha.jpg" width="640" height="266" /></p>
 
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      <p><strong>Figure</strong> Metabolic versatility or R. palustris (Harwood  et. al. (2004))</p>
 
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        When O2 is  absent or limiting, light energy can be harnessed by a photosynthetic electron  transport chain that has features similar to those used by plants and other  oxygen-evolving phototrophs <strong>(3)</strong>. During photosynthetic growth, <em>R. palustris</em> is capable of autotrophic  or heterotrophic growth using either carbon dioxide (CO2) or organic carbon  sources. <br />
 
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        <strong>Biotechnological  potential</strong><br />
 
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        <em>R. palustris </em>is an excellent candidate for use in a wide  variety of biotechnological applications because of a wide range of  regulation systems that allow it to sense environmental conditions.</p>
 
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    <p><img src="images/Cha2.jpg" width="640" height="474" /></p>
 
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    <p><strong>Why synthetic biology in <em>R. palustris</em>?</strong></p>
 
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    <p>The application of Synthetic Biology in R. palustris  could help to exploit the biotechnological potential of this organism. We want  to explore the functioning of 2 orthologous regulation systems that respond to  oxygen and light inspired in <em>Rhodobacter  sphaeroides </em>regulatory systems.</p>
 
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    <p><img src="images/Cha3.jpg" width="640" height="463" /></p>
 
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    <p>1. Hunter CN, Daldal F, Thurnauer MC, Beatty JT:  (2009) <strong>The Purple Phototrophic Bacteria</strong>.  Springer; 200928.<em> pp. 707–725.</em> <br />
 
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      2.  Harwood  et. al. (2004) <strong>Complete genome sequence of the metabolically versatile  photosynthetic bacterium <em>Rhodopseudomonas palustris</em></strong>, Nature Biotechnology Volume 2, Number 1,  January 2004<br />
 
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      3. Imam S., Yilmaz S., Sohmen Y, Gorzalski A., Reed J.  Noguera D., Donohue T. (2011)<strong> iRsp1095:  A genome-scale reconstruction of theRhodobacter sphaeroides metabolic network </strong>BMC  Systems Biology 2011, 5:116 </p>
 
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Latest revision as of 00:18, 27 September 2012