Team:HUST-China/Achievements/Modeling

From 2012.igem.org

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<h3>4>Simulating the Quorum-Sensing and aggregation by constructing software named HUST-CAL 1.0</h4>

Revision as of 22:33, 26 September 2012

logo

HUST CHINA


Modeling Achievements

Not only have we design bacterial batteries, but we modeled simplified pathway of bacterial batteries. In the project, we have constructed three models, the single cell model, multi-cell model, and CCDB-related model. All of these can co-attribute to this pathway.

1>Design of bacterial batteries

2>Simulation and calculation of the distribution of proton in panel

*Formation of hydrogen ion's concentration gradient
In our model, we first put up an idea about building a concentration gradient of hydrogen ions by wasted water. The two with different PH values are lay at opposite places, and were linked with each other by a narrow bucket, which can form the concentration gradient.

3>Quorum-Sensing

Simulate and calculate different molecules or cells with time-dependent concentration, i.e., AHL, cell-density, CCDB. The results can be showed in the three figures below.

1,AHL-time


2,Cell density-time


3,CCDB-time


4>Simulating the Quorum-Sensing and aggregation by constructing software named HUST-CAL 1.0


Figure 1. The distribution of bacteria in panel based on the rule of quorum-sensing

Figure 2. The distribution of bacteria in panel on the rule of aggregation
© Huazhong University of Science and Technology.