Team:Osaka

From 2012.igem.org

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This is a template page. READ THESE INSTRUCTIONS.
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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
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You <strong>MUST</strong> have all of the pages listed in the menu below with the names specified. PLEASE keep all of your pages within your teams namespace. 
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|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
 
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|[[Image:Osaka_logo.png|200px|right|frame]]
 
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''Tell us more about your project.  Give us background.  Use this as the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
 
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|[[Image:Osaka_team.png|right|frame|Your team picture]]
 
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|align="center"|[[Team:Osaka | Team Osaka]]
 
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!align="center"|[[Team:Osaka|Home]]
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!align="center"|[[Team:Osaka/Team|Team]]
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!align="center"|[https://igem.org/Team.cgi?year=2012&team_name=Osaka Official Team Profile]
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!align="center"|[[Team:Osaka/Project|Project]]
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<b>Our team project:<font color="red">BIO-DOSIMETER</font></b>                   
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!align="center"|[[Team:Osaka/Parts|Parts Submitted to the Registry]]
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!align="center"|[[Team:Osaka/Modeling|Modeling]]
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!align="center"|[[Team:Osaka/Notebook|Notebook]]
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!align="center"|[[Team:Osaka/Safety|Safety]]
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!align="center"|[[Team:Osaka/Attributions|Attributions]]
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<p><img src="https://static.igem.org/mediawiki/2011/4/48/Osaka_ecoli_copy.jpg" width="800" height="300"></p>
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In the modern world, radioactivity is a phenomena well understood by science, and harnessed by engineering for nuclear power generation, radiology in medicine, radioisotopic labeling in biological studies and numerous other applications. However, it is an undeniable fact that the ionizing radiation resulting from radioactive decay may cause critical effects on biological creatures, from the smallest bacteria to plants and animals including humans.
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On March 11, 2011, the Great East Japan Earthquake struck off the coast of Eastern Japan and triggered a series of equipment failures, nuclear meltdowns, and releases of radioactive materials at the Fukushima 1 Nuclear Power Plant, leading to a nationwide nuclear crisis. <img src="https://static.igem.org/mediawiki/2011/b/b9/Nuclear_1.jpg.jpg" height="250" align="right" alt="the crisis of Japanese nuclea plants">While ‘Grays’, ‘Sieverts’, ‘exposure’, ‘equivalent dosage’ and other related terms and units became referred daily in the media, much of the general populace remained ignorant of their meanings and significance. The need for low-cost, portable and easy-to-use dosimeters was apparent as measurements of radiation exposure could only be conducted at dedicated installations spaced far apart and the numbers reported only infrequently.
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Hence, this year, iGEM Osaka decided to tackle the building of a biological dosimeter. We attempted to modularly transfer radiation-response and DNA repair genes from the extremophilic bacterium <i>Deinococcus radiodurans</i> to the well-characterized, easily cultivable chassis of <i>Escherichia coli</i>. From there our efforts branched out into (1) evaluating radioresistance conferred by the heterologous genes, and (2) connecting the radiation/DNA damage response system to visible outputs such as color pigment production.
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 ■ Sponsors                       
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<a href="https://2011.igem.org/Team:Osaka/we_love_JAPAN">
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<img src="https://static.igem.org/mediawiki/2011/8/86/Osaka_kokki_3.jpg" width="240" height="160" ALIGN="right"></a>
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<p><a href="http://www.cosmobio.co.jp">
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<img src="https://static.igem.org/mediawiki/2011/3/3a/Osaka_sponsors.jpg"></a></p>
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<p><a href="http://www.osaka-u.ac.jp/en/index.html">
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<img src="https://static.igem.org/mediawiki/2011/3/31/OU_logo.gif"></a></p>
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<br>Contact us : xiaoshunmeng@gmail.com
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Revision as of 00:37, 21 June 2012




Our team project:BIO-DOSIMETER






In the modern world, radioactivity is a phenomena well understood by science, and harnessed by engineering for nuclear power generation, radiology in medicine, radioisotopic labeling in biological studies and numerous other applications. However, it is an undeniable fact that the ionizing radiation resulting from radioactive decay may cause critical effects on biological creatures, from the smallest bacteria to plants and animals including humans.

On March 11, 2011, the Great East Japan Earthquake struck off the coast of Eastern Japan and triggered a series of equipment failures, nuclear meltdowns, and releases of radioactive materials at the Fukushima 1 Nuclear Power Plant, leading to a nationwide nuclear crisis. the crisis of Japanese nuclea plantsWhile ‘Grays’, ‘Sieverts’, ‘exposure’, ‘equivalent dosage’ and other related terms and units became referred daily in the media, much of the general populace remained ignorant of their meanings and significance. The need for low-cost, portable and easy-to-use dosimeters was apparent as measurements of radiation exposure could only be conducted at dedicated installations spaced far apart and the numbers reported only infrequently.

Hence, this year, iGEM Osaka decided to tackle the building of a biological dosimeter. We attempted to modularly transfer radiation-response and DNA repair genes from the extremophilic bacterium Deinococcus radiodurans to the well-characterized, easily cultivable chassis of Escherichia coli. From there our efforts branched out into (1) evaluating radioresistance conferred by the heterologous genes, and (2) connecting the radiation/DNA damage response system to visible outputs such as color pigment production.

 ■ Sponsors



Contact us : xiaoshunmeng@gmail.com