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| | <div class="col col23"> | | <div class="col col23"> |
| | <h2>Welcome To TTEC!</h2> | | <h2>Welcome To TTEC!</h2> |
| - | <p>TTEC(transcriptional terminator efficiency calculation) is the name of our software.</p> | + | <p>We developed the Transcriptional Terminator Efficiency Calculator.</p> |
| | <p>It is important that transcription is imperfectly terminated at some terminators so that the ratio of the amount of mRNA transcribed from upstream and that from downstream of the terminator is controlled. This is qualified as terminator efficiency. </p> | | <p>It is important that transcription is imperfectly terminated at some terminators so that the ratio of the amount of mRNA transcribed from upstream and that from downstream of the terminator is controlled. This is qualified as terminator efficiency. </p> |
| | <p>We studied the Transcription Terminators which regulate the gene expression. We have developed a free energy based theoretical model to calculate the terminator efficiency from nucleotide sequences. Then, we did some experiment and measured the efficiency of more than 100 terminators to validate our model. Our work is by far the most comprehensive study on terminator efficiency.</p> | | <p>We studied the Transcription Terminators which regulate the gene expression. We have developed a free energy based theoretical model to calculate the terminator efficiency from nucleotide sequences. Then, we did some experiment and measured the efficiency of more than 100 terminators to validate our model. Our work is by far the most comprehensive study on terminator efficiency.</p> |
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| | <ul class="tmo_ul_list"> | | <ul class="tmo_ul_list"> |
| | <li><a href="http://www.terminatorefficiency.com/"><h3>TTEC-Website</h3></a></li> | | <li><a href="http://www.terminatorefficiency.com/"><h3>TTEC-Website</h3></a></li> |
| - | <li><a href="https://2012.igem.org/Team:SUSTC-Shenzhen-B/Tutorial"><h3>Tutorial</h3></a></li> | + | <li><a href="https://2012.igem.org/Team:SUSTC-Shenzhen-B/Tutorial"><h3>Website Tutorial</h3></a></li> |
| | </ul> | | </ul> |
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Welcome To TTEC!
We developed the Transcriptional Terminator Efficiency Calculator.
It is important that transcription is imperfectly terminated at some terminators so that the ratio of the amount of mRNA transcribed from upstream and that from downstream of the terminator is controlled. This is qualified as terminator efficiency.
We studied the Transcription Terminators which regulate the gene expression. We have developed a free energy based theoretical model to calculate the terminator efficiency from nucleotide sequences. Then, we did some experiment and measured the efficiency of more than 100 terminators to validate our model. Our work is by far the most comprehensive study on terminator efficiency.
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