Team:Dundee/Modelling

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Revision as of 19:22, 17 September 2012

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Lorem ipsum dolor sit amet, consectetur adipiscing elit. Sed semper metus eu dui rutrum sed fringilla mauris mattis. In quis ipsum eu purus accumsan tempor. Nulla ipsum nibh, aliquet at faucibus sit amet, suscipit nec erat. Ut in tincidunt risus. Class aptent taciti sociosqu ad litora torquent per conubia nostra, per inceptos himenaeos. Nulla facilisi. Sed vulputate lacinia ante, non tincidunt orci feugiat ac. Nulla cursus turpis non orci aliquam faucibus. In hac habitasse platea dictumst.

Pellentesque dictum semper blandit. Nunc non tellus tellus, at sodales enim. Nam porttitor nisi ligula, et venenatis lacus. Quisque in sem nec justo lacinia dignissim. Proin ac augue id turpis cursus iaculis. Phasellus tincidunt scelerisque erat sed tempus. Suspendisse venenatis vulputate mi. Mauris blandit adipiscing odio, ac tincidunt felis tempus ac.

Donec eu ante nec est malesuada gravida et non nisi. Nunc posuere cursus magna. Proin eu turpis est. Donec et velit ac dolor luctus laoreet. Proin pulvinar velit vitae libero sagittis aliquet auctor justo iaculis. Quisque in eros at leo tempus tincidunt. Ut blandit sapien et quam venenatis feugiat. Maecenas commodo pellentesque metus, vitae rhoncus lorem pulvinar vel. Suspendisse gravida, purus eu aliquam tincidunt, magna eros scelerisque elit, ut faucibus erat justo eu orci. Sed placerat nunc nec leo imperdiet lacinia. Mauris porta dignissim cursus.

Endolysin and C. diff

ODE – E. coli and C. diff

PDE- E. coli and C. diff

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-                 <I>Clostridium difficile</I> (<I>C. diff</I>) is a gram-positive bacterium that lives naturally in the gut. In healthy individuals, the levels of <I>C. diff</I>  are kept constant due to competition with other naturally occurring bacterial species in the gut flora. However, when patients receive large doses of antibiotics, competing gut flora can be wiped out. This can allow the population of <I>C. diff</I>  to increase to a level where infection can be caused and in some cases resulting in severe colitis. <I>C. diff</I>  has therefore become a major cause of hospital acquired infections, with, for example, some 2645 patients in hospitals in England and Wales found suffering from <I>C. diff</I>  induced colitis in March-May 2010.
+                 Lorem ipsum dolor sit amet, consectetur adipiscing elit. Sed semper metus eu dui rutrum sed fringilla mauris mattis. In quis ipsum eu purus accumsan tempor. Nulla ipsum nibh, aliquet at faucibus sit amet, suscipit nec erat. Ut in tincidunt risus. Class aptent taciti sociosqu ad litora torquent per conubia nostra, per inceptos himenaeos. Nulla facilisi. Sed vulputate lacinia ante, non tincidunt orci feugiat ac. Nulla cursus turpis non orci aliquam faucibus. In hac habitasse platea dictumst.<br><br>
-<br><br><img src="https://static.igem.org/mediawiki/2012/e/e9/Cdiff.jpg"><br><br>
+Pellentesque dictum semper blandit. Nunc non tellus tellus, at sodales enim. Nam porttitor nisi ligula, et venenatis lacus. Quisque in sem nec justo lacinia dignissim. Proin ac augue id turpis cursus iaculis. Phasellus tincidunt scelerisque erat sed tempus. Suspendisse venenatis vulputate mi. Mauris blandit adipiscing odio, ac tincidunt felis tempus ac.<br><br>
-Infection rates have also been high at Dundee's Ninewells Hospital, which is affiliated with the University of Dundee. As a result, in 2010 a ward at the hospital was closed following the deaths of 5 elderly patients due to <I>C. diff</I>  infections. So for us, this is also a very local health problem. Up until now, there have been two ways of treating this problem: prescribe more antibiotics, with the added difficulty of possibly causing more resistance to build-up, or by means of faecal transplant. A faecal transplant involves the faeces of a person close to the patient being transplanted directly into the patient's colon or through a drip into the stomach. This has been proven to be effective in test cases, but is obviously an unsavoury form of treatment for many patients and so the idea of creating an alternative gave rise to this project.
+Donec eu ante nec est malesuada gravida et non nisi. Nunc posuere cursus magna. Proin eu turpis est. Donec et velit ac dolor luctus laoreet. Proin pulvinar velit vitae libero sagittis aliquet auctor justo iaculis. Quisque in eros at leo tempus tincidunt. Ut blandit sapien et quam venenatis feugiat. Maecenas commodo pellentesque metus, vitae rhoncus lorem pulvinar vel. Suspendisse gravida, purus eu aliquam tincidunt, magna eros scelerisque elit, ut faucibus erat justo eu orci. Sed placerat nunc nec leo imperdiet lacinia. Mauris porta dignissim cursus.
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