Team:LMU-Munich/Application/Protein Screening

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==Protein Screening==



<p align="justify">[http://www.ncbi.nlm.nih.gov/pubmedterm=screening%20libraries%20to%20identify%20proteins%20with%20desired%20binding%20activities%20using%20a%20split%20gfp%20reassembeling%20assay Designer protein] molecules, which bind their desired targets specifically, have numerous uses. Designer proteins are frequently created by constructing and screening libraries of mutated protein variants. Proteins with desired properties are selected for in this method. Despite the success of the method, it is labor intensive and limited in throughput. Individual mutated proteins must be tracked throughout the entire screening process. Our [https://2012.igem.org/Team:LMU-Munich/Spore_Coat_Proteins '''Sporo'''beads] would eliminate the need to track protein mutants, allowing researchers to screen huge quantities of mutated proteins, only identifying and sequencing these proteins after successful screening. Figures 1 and 2 offer schematics of the process of using '''Sporo'''beads for protein screening for tests and affinities.</p>


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<font color="#000000"; size="2">Fig. 1: '''The simple protein-screening process in our Sporobeads'''. </font>
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<font color="#000000"; size="2">Fig. 2: '''The simple protein-screening process in our Sporobeads''' using affinity binding as a requisite. </font>
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