Team:Trieste

            
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	    <h1 id="h1_lf" class="main_tit"><div>Our Project</div></h1>
            <h1 id="h1_mn" class="main_tit"><div>Quick Links</div></h1>
            <h1 id="h1_rt" class="main_tit"><div>The Team</div></h1>
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		<h2>We present you the Jolly JoCare</h2>
		
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				<strong>Background</strong><br/>Recent studies have evidenced that having a beneficial and healthy
				intestinal microflora is very important for human health.<br/>
                               <br/>
                                <strong>Project</strong><br/>
                                 Our
				aim is to modify a bacteria normally found in human gut and
				create a safe, controllable and versatile molecular platform
				which can be used to produce a wide range of molecules	leading
				to a beneficial probiotic. For this purpose we have chosen the
				E. coli strain Nissle 1917 which has been used for many years as
				a probiotic. We designed a robust gene guard system regulated
				by a novel and easy to control inducible cumate switch that
				activates the production of a human antimicrobial peptide LL-37
				that can kill the bacteria and also avoid horizontal transfer.
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                                <br/>
		    <strong>Applications</strong><br/>The safe probiotic constructed here can be used to produce nutritious, preventive or therapeutic molecules. For example, we have used it to produce an antibody against the emerging virus, Norovirus. 
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                            <div class="title">Achievements</div>
                            <div class="date"><center><img src="https://static.igem.org/mediawiki/igem.org/a/a4/Goldts.png" width="70px"/><centeer></div>
                            <div class="intro"><a href="https://2012.igem.org/Team:Trieste/extra/ach"target="_blank"> Quick link </a> to our judging form and Achievements summary  </div>
			    <div class="read_more"><a href="https://2012.igem.org/Team:Trieste/extra/ach"target="_blank">a</a></div>
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                            <div class="title">Project</div>
                            <div class="date"><center><img src="https://static.igem.org/mediawiki/2012/8/8a/Diapositiva1.jpg"width="100px"/></center></div>
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				 <a href="https://2012.igem.org/Team:Trieste/project/overview"target="_blank">Overview </a> - Have a look to our Jolly JoCare Project at a glance!
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			    <div class="read_more"><a href="https://2012.igem.org/Team:Trieste/project/overview"target="_blank">a</a></div>
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                            <div class="title">Data</div>
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                            <div class="intro"><a href="https://2012.igem.org/Team:Trieste/data"target="_blank">Click here</a> to reach our summary page</div>
			    <div class="read_more"><a href="https://2012.igem.org/Team:Trieste/data"target="_blank">a</a></div>
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			<h2>Contact us</h2>
			<p>For other information, write to:</p>
                    <a href="mailto:igem2012@gmail.com" class="btn">igem2012@gmail.com</a>
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