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Team:University College London/Module 6/Conclusion
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We have successfully transformed our cells to produce a periplasmic nuclease, a necessary feature to prevent transformation of wild-type cells in the marine environment. Furthermore, we have proven that this BioBrick does not adversely affect the viability of our cells, allowing it to be utilised as part of a containment system for engineered cells. | We have successfully transformed our cells to produce a periplasmic nuclease, a necessary feature to prevent transformation of wild-type cells in the marine environment. Furthermore, we have proven that this BioBrick does not adversely affect the viability of our cells, allowing it to be utilised as part of a containment system for engineered cells. | ||
| - | Future work would attempt to construct a three-fold | + | Future work would attempt to construct a three-fold containment system, in order to create a more robust system capable of prevent other mechanisms of horizontal gene transfer, such as transduction and bacterial conjugation. |
Revision as of 14:26, 26 September 2012
Module 6: Containment
Description | Design | Construction | Characterisation | Modelling | Results | Conclusions
Conclusion
We have successfully transformed our cells to produce a periplasmic nuclease, a necessary feature to prevent transformation of wild-type cells in the marine environment. Furthermore, we have proven that this BioBrick does not adversely affect the viability of our cells, allowing it to be utilised as part of a containment system for engineered cells.
Future work would attempt to construct a three-fold containment system, in order to create a more robust system capable of prevent other mechanisms of horizontal gene transfer, such as transduction and bacterial conjugation.
