Team:Tec-Monterrey EKAM

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Tec de Monterrey: Team Ekam
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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
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Project Ekam
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|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
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|Four Biotech students from the arid lands of Monterrey, México.
|[[Image:Tec-Monterrey_EKAM_logo.png|200px|right|frame]]
|[[Image:Tec-Monterrey_EKAM_logo.png|200px|right|frame]]
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''Tell us more about your project. Give us background.  Use this as the abstract of your project. Be descriptive but concise (1-2 paragraphs)''
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''Modular Terpenoid Biofactory
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This project uses the yeast ''P. pastoris'' as a cellular factory to produce terpenoids. Terpenoids are hydrocarbon molecules that serve many purposes; they have anti-inflammatory, anti-neoplastic, anti-malarial and anti-bacterial qualities and are also of use in the cosmetic and chemical industries. Most terpenoids come from plants and, usually, their yields are low. The goal is to increase the yield through the use of synthetic biology, making a bio-brick platform which could be suited to specific ends and further expanded and controlled.
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Taking advantage of the existent Mevalonate pathway in ''P. pastoris'' (the metabolic route which provides the precursors to the terpenoid biosynthesis) -engineered to limit negative feedback loops- the terpenoids of interest will be produced by introducing the appropriate synthases. By means of siRNA silencing, the sterol pathway will be controlled to insure that most of the substrates will be channeled to terpenoid production.''
|[[Image:Tec-Monterrey_EKAM_team.png|right|frame|Your team picture]]
|[[Image:Tec-Monterrey_EKAM_team.png|right|frame|Your team picture]]
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Revision as of 00:09, 8 June 2012

Tec de Monterrey: Team Ekam

Four Biotech students from the arid lands of Monterrey, México.
Tec-Monterrey EKAM logo.png

Modular Terpenoid Biofactory

This project uses the yeast P. pastoris as a cellular factory to produce terpenoids. Terpenoids are hydrocarbon molecules that serve many purposes; they have anti-inflammatory, anti-neoplastic, anti-malarial and anti-bacterial qualities and are also of use in the cosmetic and chemical industries. Most terpenoids come from plants and, usually, their yields are low. The goal is to increase the yield through the use of synthetic biology, making a bio-brick platform which could be suited to specific ends and further expanded and controlled.

Taking advantage of the existent Mevalonate pathway in P. pastoris (the metabolic route which provides the precursors to the terpenoid biosynthesis) -engineered to limit negative feedback loops- the terpenoids of interest will be produced by introducing the appropriate synthases. By means of siRNA silencing, the sterol pathway will be controlled to insure that most of the substrates will be channeled to terpenoid production.

Your team picture
Team Tec-Monterrey_EKAM


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