Team:Tec-Monterrey EKAM

From 2012.igem.org

(Difference between revisions)
Line 2: Line 2:
<head>
<head>
<meta http-equiv="content-type" content="text/html;charset=utf-8" />
<meta http-equiv="content-type" content="text/html;charset=utf-8" />
 +
<link rel="stylesheet" type="text/css" href="css/ekam.css"/>
 +
<script type="text/javascript" src="http://ajax.googleapis.com/ajax/libs/jquery/1.6.2/jquery.min.js"></script>
 +
<!----///////////////////////////////////////////////////////////////////////////////--->
<!----///////////////////////////////////////////////////////////////////////////////--->
<style>
<style>
Line 23: Line 26:
#top-section{
#top-section{
-
display:none;
+
display:none;
}
}
.firstHeading{
.firstHeading{
-
display:none;
+
display:none;
}
}
#content{
#content{
-
//display:none;
+
//display:none;
-
width: 100%;
+
width: 100%;
}
}
.visualClear{
.visualClear{
-
display:none;
+
display:none;
}
}
#catlinks{
#catlinks{
-
display:none
+
display:none;
}
}
#footer-box{
#footer-box{
-
display: none;
+
display: none;
}
}
/***BRRRRRRRRRR!**/
/***BRRRRRRRRRR!**/
*{
*{
-
font-family: "Palatino Linotype", "Book Antiqua", Palatino, serif;
+
font-family: "Palatino Linotype", "Book Antiqua", Palatino, serif !important;
 +
font-size:1em !important;
}
}
Line 129: Line 133:
text-decoration:none;
text-decoration:none;
font-weight: bold;
font-weight: bold;
 +
//text-transform: uppercase;
}
}
 +
/*.navigationLink:hover{
 +
width: 150px;
 +
height: 90px;
 +
font-size: 1.3em;
 +
//background-color:#fff;
 +
//color: #45172A;
 +
}*/
#ON{
#ON{
background-color: #242329;
background-color: #242329;
Line 139: Line 151:
#subMenu{
#subMenu{
height: 100%;
height: 100%;
-
width:15%;
+
width:130px;
margin-top:0px;
margin-top:0px;
-
margin-left:2%;
+
margin-left:20px;
-
margin-right:2%;
+
float:left;
float:left;
}
}
#sideBar{
#sideBar{
-
height: 240px;
+
height: 100%;
list-style-type: none;
list-style-type: none;
padding: 0;
padding: 0;
Line 163: Line 174:
height: 45px;
height: 45px;
padding: 5px;
padding: 5px;
 +
//border: 1px solid #38091C;
background-color: #45172A;
background-color: #45172A;
color: #fff;
color: #fff;
Line 168: Line 180:
text-decoration:none;
text-decoration:none;
font-size: .7em;
font-size: .7em;
 +
//font-weight: bold;
 +
//text-transform: uppercase;
}
}
 +
/*.sideLink:hover{
 +
width: 130px;
 +
height: 60px;
 +
font-size: 1em;
 +
//background-color:#fff;
 +
//color: #45172A;
 +
}*/
#sideON{
#sideON{
background-color: #242329;
background-color: #242329;
Line 185: Line 206:
#mainPart{
#mainPart{
margin-right:15%;
margin-right:15%;
-
margin-left:15%;
+
position: absolute;
 +
left:180px;
}
}
Line 196: Line 218:
font-weight:bold;
font-weight:bold;
}
}
 +
</style>
</style>
<!----///////////////////////////////////////////////////////////////////////////////--->
<!----///////////////////////////////////////////////////////////////////////////////--->
-
<script type="text/javascript" src="http://ajax.googleapis.com/ajax/libs/jquery/1.6.2/jquery.min.js"></script>
+
 
<script type="text/javascript">
<script type="text/javascript">
/*Show sideMenu in a Fancy way*/
/*Show sideMenu in a Fancy way*/
-
$(document).ready(function(){
+
$(document).ready(function(){
$("#sideBar").hide();
$("#sideBar").hide();
$("#sideBar").slideDown("slow");
$("#sideBar").slideDown("slow");
Line 229: Line 252:
<!--<div id="headerEkam" class="centerBody">-->
<!--<div id="headerEkam" class="centerBody">-->
<!--<div id="logos" class="centerBody">-->
<!--<div id="logos" class="centerBody">-->
-
<img id="headerCover" src="https://static.igem.org/mediawiki/2012/5/5b/Ekam_header.png">
+
<img id="headerCover" src="https://static.igem.org/mediawiki/2012/5/5b/Ekam_header.png">
<!--<div id="headerLogo" > <img width="20%" src="http://animais.culturamix.com/blog/wp-content/uploads/2010/09/0310.jpg"/> </div>-->
<!--<div id="headerLogo" > <img width="20%" src="http://animais.culturamix.com/blog/wp-content/uploads/2010/09/0310.jpg"/> </div>-->
<!--<div id="headerCover" ><img width="80%" src="http://ianimals.com/animals/capybara.jpg"/></div>-->
<!--<div id="headerCover" ><img width="80%" src="http://ianimals.com/animals/capybara.jpg"/></div>-->
Line 251: Line 274:
</div>
</div>
<!--</div>-->
<!--</div>-->
 +
<div id="wikiBody">
<div id="subMenu" style>
<div id="subMenu" style>
<ul id="sideBar">
<ul id="sideBar">
Line 275: Line 299:
By means of siRNA silencing, the sterol pathway will be controlled to ensure that most of the substrates will be channeled to terpenoid production.
By means of siRNA silencing, the sterol pathway will be controlled to ensure that most of the substrates will be channeled to terpenoid production.
</p>
</p>
 +
</div>
</div>
</div>
</body>
</body>
</html>
</html>

Revision as of 20:26, 11 July 2012

Modular Terpenoid Biofactory

This project uses the yeast P. pastoris as a cellular factory to produce terpenoids. Terpenoids are hydrocarbon molecules that serve many purposes; they have anti-inflammatory, anti-neoplastic, anti-malarial and anti-bacterial qualities and are also of use in the cosmetic and chemical industries. Most terpenoids come from plants and, usually, their yields are low. The goal is to increase the yield through the use of synthetic biology, making a bio-brick platform which could be suited to specific ends and further expanded and controlled.

Taking advantage of the existent Mevalonate pathway in P. pastoris (the metabolic route which provides the precursors to the terpenoid biosynthesis) -engineered to limit negative feedback loops- the terpenoids of interest will be produced by introducing the appropriate synthases. By means of siRNA silencing, the sterol pathway will be controlled to ensure that most of the substrates will be channeled to terpenoid production.