Team:Tec-Monterrey EKAM

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<head>
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<body>
<body>
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<!--<div id="headerEkam" class="centerBody">-->
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    <div id="ekam-wrapper">
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<!--<div id="logos" class="centerBody">-->
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<div id= 'ekam_container'>
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<div id="ekam_header">
-
<!--<div id="headerLogo" > <img width="20%" src="http://animais.culturamix.com/blog/wp-content/uploads/2010/09/0310.jpg"/> </div>-->
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<div id="logo" >
-
<!--<div id="headerCover" ><img width="80%" src="http://ianimals.com/animals/capybara.jpg"/></div>-->
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<div class="ekam_moduletable">
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<!--</div>-->
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-
<div id="menu" class="centerBody">
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</div>
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<ul id="navigationBar">
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</div>
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<li><strong id="ON">Home</strong></li>
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<div id="menu">
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<li><a class="navigationLink" href="/Team:Tec-Monterrey_EKAM/Team">Team</a></li>
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<p>Home</p>
-
<!-- Mandar a Team-->
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</div>
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<li><a class="navigationLink" href="https://igem.org/Team.cgi?year=2012&amp;team_name=Tec-Monterrey_EKAM" rel="nofollow">Profile</a></li>
+
</div>
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<!---->
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<!-- END OF HEADER -->
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<li><a class="navigationLink" href="/Team:Tec-Monterrey_EKAM/Project">The Terpenoid Biofactory</a></li>
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        <!-- ===================================================== MAIN ===================================================== -->
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<li><a class="navigationLink" href="/Team:Tec-Monterrey_EKAM/Notebook" >Notebook</a></li>
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        <div id="ekam_content-area">
-
<!--Mandar a Project
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            <div id="ekam_main">
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<li><a class="navigationLink" href="/Team:Tec-Monterrey_EKAM/Parts" >Parts</a></li>
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                <!--------------------->
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<li><a class="navigationLink" href="/Team:Tec-Monterrey_EKAM/Modeling">Modeling</a></li>
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                <img id="Ekam_imagenHome" src= "https://static.igem.org/mediawiki/igem.org/e/ed/Ekam_HeaderClean.png"/>  
-
<li><a class="navigationLink" href="/Team:Tec-Monterrey_EKAM/Safety">Safety</a></li>
+
<br/>
-
<li><a class="navigationLink" href="/Team:Tec-Monterrey_EKAM/Attributions" >Attributions</a></li>
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                <div class="ekam_subMain">
-
-->
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                    <p class="safety_answer">
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</ul>
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                        <span class="safety_question">The Modular BioFactory</span>
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</div>
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                        <br/>
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<!--</div>-->
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<span style="font-weight: bold">
-
<div id="wikiBody">
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This project uses the yeast P. pastoris as a cellular factory to produce terpenoids. Terpenoids are hydrocarbon molecules that serve many purposes; they have anti-inflammatory, anti-neoplastic, anti-malarial and anti-bacterial qualities and are also of use in the cosmetic and chemical industries. Most terpenoids come from plants and, usually, their yields are low. The goal is to increase the yield through the use of synthetic biology, making a bio-brick platform which could be suited to specific ends and further expanded and controlled.
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<div id="subMenu" style>
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<br/>Taking advantage of the existent Mevalonate pathway in P. pastoris (the metabolic route which provides the precursors to the terpenoid biosynthesis) -engineered to limit negative feedback loops- the terpenoids of interest will be produced by introducing the appropriate synthases. By means of siRNA silencing, the sterol pathway will be controlled to ensure that most of the substrates will be channeled to terpenoid production.
-
<ul id="sideBar">
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</span>  
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<li><strong id="sideON">Description &gt;</strong></li>
+
                       
-
<li><a class="sideLink">We &gt;</a></li>
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                    </p>
-
<li><a class="sideLink">Will &gt;</a></li>
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                </div>  
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<li><a class="sideLink">Be &gt;</a></li>
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                <br/>               
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<li><a class="sideLink">Here &gt;</a></li>
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            </div>
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<li><a class="sideLink">Soon! &gt;</a></li>
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        </div>
-
</ul>
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        <!-- ================================================= END OF MAIN ================================================= -->
-
</div>
+
       
-
<div id="mainPart">
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        <!-- ******************* MENU *************************** -->
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<p>
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<div class="left" style="width:210px;">
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<span class="titulo">Modular Terpenoid Biofactory</span><br/><br/>
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            <div class="moduletable _menu" >
-
This project uses the yeast <i>P. pastoris</i> as a cellular factory to produce terpenoids.
+
                <div class="content-module">
-
Terpenoids are hydrocarbon molecules that serve many purposes; they have anti-inflammatory,
+
                    <ul class="menu">
-
anti-neoplastic, anti-malarial and anti-bacterial qualities and are also of use in the cosmetic and chemical industries.
+
                        <li ><a href="/Team:Tec-Monterrey_EKAM/Team" >Team</a></li>
-
Most terpenoids come from plants and, usually, their yields are low.
+
                        <li class="deeper parent"><a href="/Team:Tec-Monterrey_EKAM/Project" >Project</a>
-
The goal is to increase the yield through the use of synthetic biology,
+
<ul>
-
making a bio-brick platform which could be suited to specific ends and further expanded and controlled. <br/><br/>
+
                                <li><a href="/Team:Tec-Monterrey_EKAM/Description" >Description</a></li>
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Taking advantage of the existent Mevalonate pathway in <i>P. pastoris</i>  
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                                <li><a href="/Team:Tec-Monterrey_EKAM/Modular">BioFactory</a></li>
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(the metabolic route which provides the precursors to the terpenoid biosynthesis)
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-engineered to limit negative feedback loops- the terpenoids of interest will be produced by introducing the appropriate synthases.  
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By means of siRNA silencing, the sterol pathway will be controlled to ensure that most of the substrates will be channeled to terpenoid production.
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Latest revision as of 03:05, 27 October 2012


The Modular BioFactory
This project uses the yeast P. pastoris as a cellular factory to produce terpenoids. Terpenoids are hydrocarbon molecules that serve many purposes; they have anti-inflammatory, anti-neoplastic, anti-malarial and anti-bacterial qualities and are also of use in the cosmetic and chemical industries. Most terpenoids come from plants and, usually, their yields are low. The goal is to increase the yield through the use of synthetic biology, making a bio-brick platform which could be suited to specific ends and further expanded and controlled.
Taking advantage of the existent Mevalonate pathway in P. pastoris (the metabolic route which provides the precursors to the terpenoid biosynthesis) -engineered to limit negative feedback loops- the terpenoids of interest will be produced by introducing the appropriate synthases. By means of siRNA silencing, the sterol pathway will be controlled to ensure that most of the substrates will be channeled to terpenoid production.


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