Team:SUSTC-Shenzhen-B

From 2012.igem.org

(Difference between revisions)
Line 1: Line 1:
-
<html>
+
{|align="justify"
-
<script type="text/javascript" src='/Team:Cambridge/static/hack_splash.js?action=raw&ctype=text/javascript'></script>
+
== '''Description of Our Project''' ==
-
<script type="text/javascript" src="http://ajax.googleapis.com/ajax/libs/jquery/1.4.2/jquery.min.js"></script>
 
-
<script type="text/javascript">
 
-
$(document).ready(function() {
 
-
$('.headover h6').css("display","none");
+
*'''Motivation:'''
 +
During every synthesis, biologists need to find the proper terminator,which is a tough work . If they can deal with the problem without manual work but electronics, time will be saved a lot. We want to get the goal that when one inputs the sequence of their designed parts or the wanted terminator efficiency on their laptops,our program can immediately output the efficiency or the terminators .on the screen, which they can use directly in their productions. It will save plenty of time and work.
-
$('#Project_title').mouseover(function() {
 
-
    $('#Project_headover').stop().animate({height:'170px',top:'0px'},1000);
 
-
$('#Project_headover h6').fadeIn(500);
 
-
});
 
-
 
-
    $('#Project').mouseleave(function() {
 
-
    $('#Project_headover').stop().animate({height:'90px',top:'80px'},1000);
 
-
$('#Project_headover h6').fadeOut(500);
 
-
    });
 
-
 
-
$('#Outreach_title').mouseover(function() {
 
-
    $('#Outreach_headover').stop().animate({height:'170px',top:'0px'},1000);
 
-
$('#Outreach_headover h6').fadeIn(500);
 
-
    });
 
-
    $('#Outreach').mouseleave(function() {
+
*'''Background:'''
-
    $('#Outreach_headover').stop().animate({height:'90px',top:'80px'},1000);
+
It is important that transcription is imperfectly terminated at some terminator so that the ratio of the amount of downstream of the terminator is controlled. That synthesis in biology needs not perfect termination but a property to pass. Up to now, biologists have built a approximated system which allows us to predict the terminator efficiency of a known-sequence terminator, and even design a terminator with wanted terminator efficiency.
-
$('#Outreach_headover h6').fadeOut(500);
+
-
    });
+
-
$('#Gallery_title').mouseover(function() {
 
-
    $('#Gallery_headover').stop().animate({height:'170px',top:'0px'},1000);
 
-
$('#Gallery_headover h6').fadeIn(500);
 
-
    });
 
-
    $('#Gallery').mouseleave(function() {
+
|-
-
    $('#Gallery_headover').stop().animate({height:'90px',top:'80px'},1000);
+
|
-
$('#Gallery_headover h6').fadeOut(500);
+
*'''What to do:'''
-
    });
+
Our aim is to design a software----T.E.Q  which can achieve goals stated below:
 +
#The software contains a database of terminator efficiency. This database includes many sequences of terminator and its efficiency. All the sequences were collected by our team members.
 +
#If you enter a sequence of terminator, it can calculate the free energy and the efficiency of this sequence. Besides, it will also predict the structure of the sequence.
-
$('#Diary_title').mouseover(function() {
+
|-
-
    $('#Diary_headover').stop().animate({height:'170px',top:'0px'},1000);
+
|
-
$('#Diary_headover h6').fadeIn(500);
+
|-
-
    });
+
|
 +
|align="center"|[[Team:SUSTC-Shenzhen-B | Team SUSTC-Shenzhen-B]]
 +
|}
-
    $('#Diary').mouseleave(function() {
+
<!--- The Mission, Experiments --->
-
    $('#Diary_headover').stop().animate({height:'90px',top:'80px'},1000);
+
-
$('#Diary_headover h6').fadeOut(500);
+
-
    });
+
-
$('#Team_title').mouseover(function() {
+
{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
-
    $('#Team_headover').stop().animate({height:'170px',top:'0px'},1000);
+
!align="center"|[[Team:SUSTC-Shenzhen-B|Home]]
-
$('#Team_headover h6').fadeIn(500);
+
!align="center"|[[Team:SUSTC-Shenzhen-B/Team|Team]]
-
    });
+
!align="center"|[https://igem.org/Team.cgi?year=2012&team_name=SUSTC-Shenzhen-B Official Team Profile]
-
 
+
!align="center"|[[Team:SUSTC-Shenzhen-B/Project|Project]]
-
    $('#Team').mouseleave(function() {
+
!align="center"|[[Team:SUSTC-Shenzhen-B/Parts|Parts Submitted to the Registry]]
-
    $('#Team_headover').stop().animate({height:'90px',top:'80px'},1000);
+
!align="center"|[[Team:SUSTC-Shenzhen-B/Modeling|Modeling]]
-
$('#Team_headover h6').fadeOut(500);
+
!align="center"|[[Team:SUSTC-Shenzhen-B/Notebook|Notebook]]
-
    });
+
!align="center"|[[Team:SUSTC-Shenzhen-B/Safety|Safety]]
-
+
!align="center"|[[Team:SUSTC-Shenzhen-B/Attributions|Attributions]]
-
$('#Safety_title').mouseover(function() {
+
|}
-
    $('#Safety_headover').stop().animate({height:'170px',top:'0px'},1000);
+
-
$('#Safety_headover h6').fadeIn(500);
+
-
    });
+
-
 
+
-
    $('#Safety').mouseleave(function() {
+
-
    $('#Safety_headover').stop().animate({height:'90px',top:'80px'},1000);
+
-
$('#Safety_headover h6').fadeOut(500);
+
-
    });
+
-
 
+
-
$('#Sponsors_title').mouseover(function() {
+
-
    $('#Sponsors_headover').stop().animate({height:'170px',top:'0px'},1000);
+
-
$('#Sponsors_headover h6').fadeIn(500);
+
-
    });
+
-
 
+
-
    $('#Sponsors').mouseleave(function() {
+
-
    $('#Sponsors_headover').stop().animate({height:'90px',top:'80px'},1000);
+
-
$('#Sponsors_headover h6').fadeOut(500);
+
-
    });
+
-
+
-
  });
+
-
 
+
-
</script>
+
-
 
+
-
+
-
<noscript>
+
-
<link rel='stylesheet' type='text/css' href='/Team:Cambridge/static/wiki_splash.css?action=raw&ctype=text/css' />
+
-
<link rel='stylesheet' type='text/css' href='/Team:Cambridge/static/hack.css?action=raw&ctype=text/css' />
+
-
</noscript>
+
-
 
+
-
<div id='cam_page'>
+
-
<div id='cam_loading'>
+
-
  <div>Loading...</div>
+
-
</div>
+
-
 
+
-
<div id='cam_topbar' class='cam-box'>
+
-
<div style='margin: 0px 12px; width:160px; float: left;'>
+
-
<div class='cam-ui-icon cam-ui-icon-igem'></div>
+
-
<a href='https://2012.igem.org/Main_Page'>
+
-
iGEM HQ
+
-
</a>
+
-
</div>
+
-
<div style='margin: 0px 12px;float:left;'>
+
-
<div class='cam-ui-icon cam-ui-icon-edit'></div>
+
-
<a id='edit-link' class='cam-external' href='#'>
+
-
Page Source
+
-
</a>
+
-
                <div class='cam-ui-icon cam-ui-icon-edit'></div>
+
-
<a id='edit-intro-link' class='cam-external' href='#'>
+
-
Intro Source
+
-
</a>
+
-
</div>
+
-
<div id='cam_login_status' style='margin: 0px 12px;float:right;'>
+
-
  <span id='logged_out'>
+
-
<div class='cam-ui-icon cam-ui-icon-key'></div>
+
-
<a id='login-link' class='cam-external' href='#'>
+
-
Login
+
-
</a>
+
-
  </span>
+
-
  <span id='logged_in' style='display:none;'>
+
-
<div class='cam-ui-icon cam-ui-icon-user'></div>
+
-
<a id='user-link' class='cam-external' href='#'>
+
-
+
-
</a>
+
-
<div class='cam-ui-icon cam-ui-icon-user'></div>
+
-
<a id='account-link' class='cam-external' href='https://igem.org/User_Information'>
+
-
My Account
+
-
</a>
+
-
<div class='cam-ui-icon cam-ui-icon-key'></div>
+
-
<a id='logout-link' class='cam-external' href='/wiki/index.php?title=Special:UserLogout'>
+
-
Logout
+
-
</a>
+
-
  </span>
+
-
</div>
+
-
</div>
+
-
 
+
-
<div id = "wrapper">
+
-
 
+
-
<div id = 'container' class = 'maincontainer'>
+
-
<div id = "row1" class = 'row'>
+
-
 
+
-
<div id="Home" class = 'grid'>
+
-
</div>
+
-
 
+
-
<div id = "Project" class = "grid">
+
-
<div id = "Project_headover" class = "headover">
+
-
<ul class = "subtitles">
+
-
<li><a href ="https://2012.igem.org/Team:Cambridge/Project" class='cam-external'>Overview</a></li>
+
-
<li><a href ="https://2012.igem.org/Team:Cambridge/Parts" class='cam-external'>Parts </a></li>
+
-
<li><a href ="https://2012.igem.org/Team:Cambridge/Instrumentation" class='cam-external'>Instrumentation </a></li>
+
-
</ul>
+
-
<h6> Previous iGEM teams have charaterised an impressive array of inducible promoters, along with other elements of biosensing circuitry... Read More </h6>
+
-
</div>
+
-
<div id = "Project_title" class = "title">
+
-
</div>
+
-
</div>
+
-
 
+
-
<div id="Logo" class = 'grid'>
+
-
</div>
+
-
 
+
-
</div>
+
-
 
+
-
 
+
-
<div id = "row2" class = 'row'>
+
-
 
+
-
<div id = "Outreach" class = "grid">
+
-
<div id = "Outreach_headover" class = "headover">
+
-
<ul class = "subtitles">
+
-
<li> Overview </li>
+
-
<li> Human Practices </li>
+
-
<li> Outreach </li>
+
-
</ul>
+
-
<h6> Coming soon!</h6>
+
-
</div>
+
-
<div id = "Outreach_title" class = "title">
+
-
</div>
+
-
</div>
+
-
 
+
-
<div id = "Gallery" class = "grid">
+
-
<div id = "Gallery_headover" class = "headover">
+
-
<ul class = "subtitles">
+
-
<li> July </li>
+
-
<li> August </li>
+
-
<li> September </li>
+
-
</ul>
+
-
<h6> This section contains a photographic record of our progress during the past two... Read More </h6>
+
-
</div>
+
-
<div id = "Gallery_title" class = "title">
+
-
</div>
+
-
</div>
+
-
 
+
-
<div id = "Diary" class = "grid">
+
-
<div id = "Diary_headover" class = "headover">
+
-
<ul class = "subtitles">
+
-
<li><a href ="https://2012.igem.org/Team:Cambridge/Week_1" class='cam-external'> Week 1 </a></li>
+
-
<li><a href ="https://2012.igem.org/Team:Cambridge/Week_2" class='cam-external'> Week 2 </a></li>
+
-
<li><a href ="https://2012.igem.org/Team:Cambridge/Week_3" class='cam-external'> Week 3 </a></li>
+
-
<li><a href ="https://2012.igem.org/Team:Cambridge/Week_4" class='cam-external'> Week 4 </a></li>
+
-
</ul>
+
-
<h6> This is a detail record of our work during the Summer... <a href = "https://2012.igem.org/Team:Cambridge/Notebook">Read More </a></h6>
+
-
</div>
+
-
<div id = "Diary_title" class = "title">
+
-
</div>
+
-
</div>
+
-
 
+
-
</div>
+
-
 
+
-
<div id = "row3" class = 'row'>
+
-
 
+
-
<div id = "Team" class = "grid">
+
-
<div id = "Team_headover" class = "headover">
+
-
<ul class = "subtitles">
+
-
<li> <a href ="https://2012.igem.org/Team:Cambridge/Team" class='cam-external'>Team members </a></li>
+
-
<li> <a href ="https://igem.org/Team.cgi?year=2012" class='cam-external'>Official Team Profile</a></li>
+
-
<li> <a href ="https://2012.igem.org/Team:Cambridge/Attributions" class='cam-external'>Attributions </a></li>
+
-
</ul>
+
-
<h6> Click to view information about the Cambridge team advisors, team members and ... Read More </h6>
+
-
</div>
+
-
<div id = "Team_title" class = "title">
+
-
</div>
+
-
</div>
+
-
 
+
-
<div id = "Safety" class = "grid">
+
-
<div id = "Safety_headover" class = "headover">
+
-
<ul class = "subtitles">
+
-
<li><a href ="https://2012.igem.org/Team:Cambridge/Safety" class='cam-external'>Safety guidelines</a></li>
+
-
<li> Documents </li>
+
-
<li></li>
+
-
</ul>
+
-
<h6> Lab safety is always our first priority... Read More </h6>
+
-
</div>
+
-
<div id = "Safety_title" class = "title">
+
-
</div>
+
-
</div>
+
-
 
+
-
<div id = "Sponsors" class = "grid">
+
-
<div id = "Sponsors_headover" class = "headover">
+
-
<ul class = "subtitles">
+
-
<li> <a href = "https://2012.igem.org/Team:Cambridge/Sponsors" class='cam-external'>Sponsors</a></li>
+
-
<li> Special Thanks </li>
+
-
<li></li>
+
-
</ul>
+
-
<h6> We would like to express our heartfelt thanks to all the sponsors... Read More </h6>
+
-
</div>
+
-
<div id = "Sponsors_title" class = "title">
+
-
</div>
+
-
</div>
+
-
 
+
-
 
+
-
</div>
+
-
 
+
-
</div>
+
-
</div>
+
-
</div>
+
-
 
+
-
 
+
-
</html>
+

Revision as of 09:16, 22 July 2012

Description of Our Project

  • Motivation:

During every synthesis, biologists need to find the proper terminator,which is a tough work . If they can deal with the problem without manual work but electronics, time will be saved a lot. We want to get the goal that when one inputs the sequence of their designed parts or the wanted terminator efficiency on their laptops,our program can immediately output the efficiency or the terminators .on the screen, which they can use directly in their productions. It will save plenty of time and work.


  • Background:

It is important that transcription is imperfectly terminated at some terminator so that the ratio of the amount of downstream of the terminator is controlled. That synthesis in biology needs not perfect termination but a property to pass. Up to now, biologists have built a approximated system which allows us to predict the terminator efficiency of a known-sequence terminator, and even design a terminator with wanted terminator efficiency.


  • What to do:

Our aim is to design a software----T.E.Q which can achieve goals stated below:

  1. The software contains a database of terminator efficiency. This database includes many sequences of terminator and its efficiency. All the sequences were collected by our team members.
  2. If you enter a sequence of terminator, it can calculate the free energy and the efficiency of this sequence. Besides, it will also predict the structure of the sequence.
Team SUSTC-Shenzhen-B


Home Team Official Team Profile Project Parts Submitted to the Registry Modeling Notebook Safety Attributions