Our slogan: Cluster makes it faster; interaction alters the direction
Motivation
There lacks compartment in prokaryotic cells, and thus engineered enzymes diffuse in the cytoplasm, which makes certain reactions proceed at a very low speed.
Divergent biochemical pathways commonly exist in all types of organisms, but it is extremely hard to artificially control and switch the directions of these reactions.
What to do
We aim to attach enzymes involved in certain reactions to membrane proteins in order to fulfill goals stated below:
To accelerate reactions in certain biochemical pathway
To switch the biochemical pathway from one to the other through extracellular signal control
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