Team:Paris Bettencourt

From 2012.igem.org

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<h2>Welcome to Big Business 2.0</h2>
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<h2>Welcome to Paris Bettencourt iGEM team 2012</h2>
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This is <strong>Big Business 2.0</strong>, a free and fully standards-compliant CSS website template by <a href="http://www.freecsstemplates.org">FCT</a>. The pictures in this template are from <a href="http://fotogrph.com/">Fotogrph</a>. This free CSS template is released under a <a href="http://creativecommons.org/licenses/by/3.0/">Creative Commons Attributions 3.0</a> license, so you are pretty much free to do whatever you want with it (even use it commercially) provided you keep all the links in the footer intact. Aside from that, have fun with it :)
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During previous years’ competitions, many iGEM teams have developed projects that propose the application of Genetically Engineered Organisms (GEO) in natural environments. However, issues of biosafety continue to complicate and constrain the use of GEOs outside the lab. A primary concern is the Horizontal Gene Transfer (HGT) of synthetic genes to natural popultations. Various strategies have been developed to address this problem, providing varying levels of containment. However, the substantial elimination of HGT risks remains difficult or perhaps impossible.
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Our project aims to :
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- Evaluate the risk of HGT in different SynBio applications
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- Develop a new, improved containment system to expand the range of environments where GEOs can be used safely.
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To do so, we will rely on three levels of containment :
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- Physical containment with alginate capsules
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- Semantic containment using an amber supressor system
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- An improved killswitch featuring delayed population-level suicide through complete genome degradation.
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We will strive to make our system as robust against mutations as possible.
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Revision as of 10:25, 17 August 2012


iGEM Paris Bettencourt 2012


Welcome to Paris Bettencourt iGEM team 2012

During previous years’ competitions, many iGEM teams have developed projects that propose the application of Genetically Engineered Organisms (GEO) in natural environments. However, issues of biosafety continue to complicate and constrain the use of GEOs outside the lab. A primary concern is the Horizontal Gene Transfer (HGT) of synthetic genes to natural popultations. Various strategies have been developed to address this problem, providing varying levels of containment. However, the substantial elimination of HGT risks remains difficult or perhaps impossible. Our project aims to : - Evaluate the risk of HGT in different SynBio applications - Develop a new, improved containment system to expand the range of environments where GEOs can be used safely. To do so, we will rely on three levels of containment : - Physical containment with alginate capsules - Semantic containment using an amber supressor system - An improved killswitch featuring delayed population-level suicide through complete genome degradation. We will strive to make our system as robust against mutations as possible.

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During previous years’ competitions, many iGEM teams have developed projects that propose the application of Genetically Engineered Organisms (GEO) in natural environments. However, issues of biosafety continue to complicate and constrain the use of GEOs outside the lab. A primary concern is the Horizontal Gene Transfer (HGT) of synthetic genes to natural popultations. Various strategies have been developed to address this problem, providing varying levels of containment. However, the substantial elimination of HGT risks remains difficult or perhaps impossible.


Our project aims to :

- Evaluate the risk of HGT in different SynBio applications

- Develop a new, improved containment system to expand the range of environments where GEOs can be used safely.


To do so, we will rely on three levels of containment :

- Physical containment with alginate capsules

- Semantic containment using an amber supressor system

- An improved killswitch featuring delayed population-level suicide through complete genome degradation.


We will strive to make our system as robust against mutations as possible.

Team Paris_Bettencourt