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Team:Paris Bettencourt
From 2012.igem.org
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| - | <h3> | + | <h3>Deadlines</h3> |
<div class="date-list"> | <div class="date-list"> | ||
<ul class="list date-list"> | <ul class="list date-list"> | ||
| - | <li class="first"><span class="date"> | + | <li class="first"><span class="date">9/3/12</span> Regional Jamboree attendance fee due</li> |
| - | <li><span class="date"> | + | <li><span class="date">9/3/12</span> <a href="/Judging/Track_Selection">Track selection due </a></li> |
| - | <li><span class="date"> | + | <li><span class="date">9/3/12</span> <a href="/Jamboree/Project_abstract">Project abstracts due </a></li> |
| - | <li class="last"><span class="date"> | + | <li class="last"><span class="date">9/3/12</span> <a href="/Jamboree/Team_Roster">Team rosters due</a></li> |
| + | <li class="last"><span class="date">9/3/12</span> <a href="/Safety">Safety questions due </a></li> | ||
| + | <li class="last"><span class="date">9/26/12</span>Project and part documentation due, including documentation for all medal criteria </li> | ||
| + | <li class="last"><span class="date">9/26/12</span>BioBrick Part DNA due to the Registry </li> | ||
| + | <li class="last"><span class="date">9/26/12</span> <a href="#">Judging form due </a></li> | ||
| + | |||
| + | <li class="last"><span class="date">9/26/12</span>Wiki FREEZE at 11:59pm, EDT </li> | ||
| + | <li class="last"><span class="date">10/5-7/12</span>iGEM 2012 Regional Jamborees</li> | ||
| + | <li class="last"><span class="date">11/2-5/12</span>iGEM 2012 World Championship Jamboree, MIT</li> | ||
| + | |||
</ul> | </ul> | ||
</div> | </div> | ||
Revision as of 17:03, 17 August 2012
- Main
- Team
- Project
- Achievements
- Human Practice
- Safety
- Notebook
- Attributions
Overview
Delay system
Semantic containment
Restriction enzyme system
MAGE
Suicide system
Encapsulation
Synthetic import domain
Safety Questions
Safety AssessmentAbstract
During previous years’ competitions, many iGEM teams have developed projects that propose the application of Genetically Engineered Organisms (GEO) in natural environments. However, issues of biosafety continue to complicate and constrain the use of GEOs outside the lab. A primary concern is the Horizontal Gene Transfer (HGT) of synthetic genes to natural popultations. Various strategies have been developed to address this problem, providing varying levels of containment. However, the substantial elimination of HGT risks remains difficult or perhaps impossible.
Our project aims to :
- Evaluate the risk of HGT in different SynBio applications
- Develop a new, improved containment system to expand the range of environments where GEOs can be used safely.
To do so, we will rely on three levels of containment :
- Physical containment with alginate capsules
- Semantic containment using an amber supressor system
- An improved killswitch featuring delayed population-level suicide through complete genome degradation.
We will strive to make our system as robust against mutations as possible.
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