Team:Northwestern/Project

From 2012.igem.org

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<p>Each team must clearly attribute work done by the team on this page.  They must distinguish work done by the team from work done by others, including the host labs, advisors, instructors, graduate students, and postgraduate masters students.
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<h1>Phytase Probiotic</h1>
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<h1>Overall project</h1>
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<p>[abstract goes here]
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<p>Tell us more about your project. Give us background. Use this is the abstract of your project. Be descriptive but concise (1-2 paragraphs)
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<h2>Purpose</h2>
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<p>Our team focused on ameliorating nutrient deficiencies in developing countries. The three main nutrient deficiency disorders listed by the World Health Organization are vitamin A deficiency (VAD), iodine deficiency disorder (IDD) and iron deficiency anemia (IDA). We chose to focus on iron deficiency anemia, which is "the most common and widespread nutritional disorder in the world."
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<h2>Project Details</h2>
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<p><a href="http://www.chalmers.se/chem/EN/divisions/food-science/research">Research has been done in low-income countries</a> to demonstrate that iron deficiency is not a result a lack of iron in the diet, but rather a lack of bioavailability of the iron within the diet. The lack of bioavailability is due to phytate chelating the iron into a state that the body cannot absorb. Phytate (or phytic acid) <a href="http://en.wikipedia.org/wiki/Phytate">is the principal form of storage of phosphorous in many plant tissues.</a>  
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<h3>Part 2</h3>
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<h2>The Experiments</h2>
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<p>Phytase is an enzyme produced by bacteria and fungi that breaks down phytic acid. We plan on producing a probiotic that will release phytase into the body, thus increasing the bioavailability of iron.
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<h3>Part 3</h3>
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<h2>Implementation</h2>
<h2>Results</h2>
<h2>Results</h2>

Revision as of 01:57, 5 September 2012

Phytase Probiotic

[abstract goes here]

Purpose

Our team focused on ameliorating nutrient deficiencies in developing countries. The three main nutrient deficiency disorders listed by the World Health Organization are vitamin A deficiency (VAD), iodine deficiency disorder (IDD) and iron deficiency anemia (IDA). We chose to focus on iron deficiency anemia, which is "the most common and widespread nutritional disorder in the world."

Research has been done in low-income countries to demonstrate that iron deficiency is not a result a lack of iron in the diet, but rather a lack of bioavailability of the iron within the diet. The lack of bioavailability is due to phytate chelating the iron into a state that the body cannot absorb. Phytate (or phytic acid) is the principal form of storage of phosphorous in many plant tissues.

Phytase is an enzyme produced by bacteria and fungi that breaks down phytic acid. We plan on producing a probiotic that will release phytase into the body, thus increasing the bioavailability of iron.

Implementation

Results

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