Team:NTNU Trondheim/Equations

From 2012.igem.org

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!colspan="3"|Vgb promoter
!colspan="3"|Vgb promoter
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|ø -> FNR
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|Constant production of FNR
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|FNR -> ø
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|0.001
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|Constant degradation of FNR
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|ø -> ArcA
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|1
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|Constant production of ArcA
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|ArcA -> ø
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|0.001
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|Constant degradationof ArcA
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Revision as of 10:34, 13 August 2012

NTNU IS B.A.C.K.
Bacterial Anti-Cancer-Kamikaze

Model equations
Reaction Propensity Comments
Lldr promoter
ø -> Lldr 0.1 Constant production of Lldr
Lldr -> ø 0.0001 Constant degradation of Lldr relative to the creation of Lldr giving a molecule number of 1000.
2 Lldr -> Lldr2 3 Dimerization of Lldr
Lldr2 -> 2 Lldr 100 Undimerization of Lldr giving a majority of Lldr in dimer.
Lldr2 -> Lldr 0.0001 Degradation of Lldr dimer.
Lldr2 + Lact -> Lldr2Lact 0.0001 Binding of lactate to Lldr dimer. Lactate is notconsumed.
Lldr2Lact -> Lldr2 1 Unbinding of Lactate to dimer
Lldr2Lact -> Lldr 0.0001 Degradation of Lldr in Lldr-Lactate complex
Lldr2 + pLact -> pLactLldr2 1 Binding of dimer to lld promoter
pLactLldr2 -> Lldr2 + pLact 0.1 Unbinding of dimer to promoter
pLactLldr2 -> Lldr + pLact 0.0001 Degradation of Lldr bound to prooter.
pLactLldr2 + Lact -> pLactLldr2Lact + Lact 0.0001 Binding of lactate to promoter dimer complex.
pLactLldr2Lact -> pLactLldr2 1 Release of lactate from promoter dimer complex.
pLactLldr2Lact -> pLactLldr2Lact + mLuxi 0.005 Transcription of activated promoter gives LuxI mRNA
mLuxI -> ø 0.0025 Degradation of LuxI mRNA
mLuxI -> mLuxI + LuxI 0.0167 Translation of LuxI mRNA
LuxI -> ø 0.0002814 Degradation of LuxI
Vgb promoter
ø -> FNR 1 Constant production of FNR
FNR -> ø 0.001 Constant degradation of FNR
ø -> ArcA 1 Constant production of ArcA
ArcA -> ø 0.001 Constant degradationof ArcA
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