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Team:MIT/ResultsOverview
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| + | The MIT iGEM team set out to bring aspects from the fields of DNA computing and synthetic biology together. Over the past few months we have: | ||
| + | * established the viability of RNA as an alternative processing medium to DNA | ||
| + | * demonstrated RNA strand displacement in vivo | ||
| + | * designed, modeled and tested a DNA-based NOT gate | ||
| + | * designed, modeled and tested a modular mRNA sensor, along with an inverting sensor | ||
| + | * designed, modeled and tested various forms of regulating gene expression at the RNA level using | ||
| + | ** miRNA-induced RNAi knockdown | ||
| + | ** Decoy & TuD mediated double-repression systems | ||
| + | ** self-cleaving Hammerhead ribozymes | ||
| + | |||
| + | * characterized various new MammoBlock parts for transcribing short pieces of RNA in mammalian cells, | ||
| + | |||
</div> | </div> | ||
Revision as of 02:03, 4 October 2012
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The MIT iGEM team set out to bring aspects from the fields of DNA computing and synthetic biology together. Over the past few months we have:
* established the viability of RNA as an alternative processing medium to DNA
* demonstrated RNA strand displacement in vivo
* designed, modeled and tested a DNA-based NOT gate
* designed, modeled and tested a modular mRNA sensor, along with an inverting sensor
* designed, modeled and tested various forms of regulating gene expression at the RNA level using
** miRNA-induced RNAi knockdown
** Decoy & TuD mediated double-repression systems
** self-cleaving Hammerhead ribozymes
* characterized various new MammoBlock parts for transcribing short pieces of RNA in mammalian cells,
