Team:LMU-Munich/Project

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Revision as of 11:58, 23 April 2012

The LMU-Munich team is exuberantly happy about the great success at the World Championship Jamboree in Boston. Our project Beadzillus finished 4th and won the prize for the "Best Wiki" (with Slovenia) and "Best New Application Project".

[ more news ]

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Overall project

The goal of our project BEADzillus is the production of Bacillus subtilis spores which display different proteins with special features on their surface. For example, the spore could:

- bind harmful viruses

- bind toxic metals

- bind plastic molecules

- expose enzymes

to filter fluids or for use in laboratorys.

As a safety issue we will stop spores from outgrowing. First we want to knock out several genes which are important for germination and second we want potentially outgrowing spores to be killed by a toxin they produce themselves.

Project Details

Clone Vectors

Part of establishing Bacillus subtilis to the BioBrick mode is to modify standard vectors of Bacillus.

Evaluate Promoters

Another point is to produce promoters of Bacillus subtilis in BioBrick mode and to evaluate them.

Fuse Spore Coat Proteins

Stop Germination

Results

Retrieved from "http://2012.igem.org/Team:LMU-Munich/Project"

@@ Line 22: / Line 22: @@
 == '''Overall project''' ==
-Tell us more about your project.  Give us background.  Use this is the abstract of your project.  Be descriptive but concise (1-2 paragraphs)
 The goal of our project BEADzillus is the production of ''Bacillus subtilis'' spores which display different proteins with special features on their surface.
@@ Line 37: / Line 35: @@
 to filter fluids  or for use in laboratorys.
+As a safety issue we will stop spores from outgrowing. First we want to knock out several genes which are important for germination and second we want potentially outgrowing spores to be killed by a toxin they produce themselves.
 [[File:Project draft.png|500px|left]]