Team:LMU-Munich/Bacillus Introduction

From 2012.igem.org

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<p align="justify"> In general, bacteria can be divided into two major groups that differ primarily in their cell envelope: Gram-positive and Gram-negative. ''E. coli'' is the model organism for the Gram-negative bacteria. A model organism for the Gram-positive bacteria is ''B. subtilis'', our favourite pet. The natural habitat of ''B. subtilis'' is the soil, so it is forced to adapt to numerous environmental changes. Accordingly, ''B. subtilis'' is characterized by quick and cunning reflexes and a complex lifestyle. There are many differentiations and survival strategies that ''B. subtilis'' can engage (Fig. 1): Due to its natural competence, it can take up exogenous DNA and integrate it into its genome. To be flexible to the environment and move towards nutrients or avoid toxic agents, it is motile with the aid of its peritrichous flagella. If starved some cells even become cannibals that feast on their siblings. If the conditions get too bad for survival, ''B. subtilis'' can form endospores. These are very dormant and highly stable stages that are resistent against e.g. desiccation, UV light, heat and pressure. Once these spores encounter better conditions they are able to germinate again. See this [https://2012.igem.org/Team:LMU-Munich/Germination_Stop section] for Details on germination.</p>
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<p align="justify"> In general, bacteria can be divided into two major groups that differ primarily in their cell envelope: Gram-positive and Gram-negative. ''E. coli'' is the model organism for the Gram-negative bacteria. A model organism for the Gram-positive bacteria is ''B. subtilis'', our favourite pet. The natural habitat of ''B. subtilis'' is the soil, so it is forced to adapt to numerous environmental changes. Accordingly, ''B. subtilis'' is characterized by quick and cunning reflexes and a complex lifestyle. There are many differentiations and survival strategies that ''B. subtilis'' can engage (Fig. 1): Due to its natural competence, it can take up exogenous DNA and integrate it into its genome. To be flexible to the environment and move towards nutrients or avoid toxic agents, it is motile with the aid of its peritrichous flagella. If starved some cells even become cannibals that feast on their siblings. If the conditions get too bad for survival, ''B. subtilis'' can form endospores. These are very dormant and highly stable stages that are resistant against e.g. desiccation, UV light, heat and pressure. Once these spores encounter better conditions they are able to germinate again. See this [https://2012.igem.org/Team:LMU-Munich/Germination_Stop section] for Details on germination.</p>

Revision as of 00:57, 27 September 2012

iGEM Ludwig-Maximilians-Universität München Beadzillus

Bacillus in urban culture.jpg

The LMU-Munich team is exuberantly happy about the great success at the World Championship Jamboree in Boston. Our project Beadzillus finished 4th and won the prize for the "Best Wiki" (with Slovenia) and "Best New Application Project".

IGEM HQ LMU prize.jpg

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