Team:LMU-Munich/Application/Further Applications

From 2012.igem.org

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==Further Applications==
==Further Applications==
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<p align="justify">Ultimately, the ability to express virtually any protein of interest shows great potential for laboratory work. Our '''Sporo'''beads could additionally express TAL effectors, for the binding of sequence-specific DNA stretches. This could allow simple GMO detection of food crops. Besides simply expressing proteins capable of binding elements of interest, our '''Sporo'''beads could express proteins which have enzymatic activity. The [https://2011.igem.org/Team:Washington 2011 University of Washington iGEM team] developed an enzyme, Kumamolisin, which cleaves peptides. The specific substrate of this enzyme is the specific amino acid sequence which causes reactions in individuals with Celiac disease. Such a cleaving enzyme could be used to eliminate irritants from gluten-containing food products.</p>
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<p align="justify">Ultimately, the ability to express virtually any protein of interest shows great potential for laboratory work. Our '''Sporo'''beads could for example express TAL effectors for the binding of sequence-specific DNA stretches. This could allow simple GMO detection of food crops. Besides expressing proteins capable of binding compounds or ions of interest, our '''Sporo'''beads could also display proteins which have enzymatic activity. The [https://2011.igem.org/Team:Washington 2011 University of Washington iGEM team] developed an enzyme, Kumamolisin, which cleaves peptides. The substrate of this enzyme is a specific amino acid sequence which causes reactions in individuals with Celiac disease. Such a cleaving enzyme could be used to eliminate irritants from gluten-containing food products.</p>
[[File:LMU Sporo diversity.png|left|200px]]
[[File:LMU Sporo diversity.png|left|200px]]
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<p align="justify">There are many possible applications for our [https://2012.igem.org/Team:LMU-Munich/Spore_Coat_Proteins '''Sporo'''beads], as it is possible to display all kinds of different proteins on their surface. To easily create them, we designed a [https://2012.igem.org/Team:LMU-Munich/Bacillus_BioBricks/Sporovector '''Sporo'''vector] in which you just have to insert the gene encoding your fusion protein of choice. Since there are so many possible applications, we illustrate three examplary ideas for future '''Sporo'''beads in the following section:</p>
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== '''Sporo'''vector ==
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<p align="justify">There are many possible applications for our [https://2012.igem.org/Team:LMU-Munich/Spore_Coat_Proteins '''Sporo'''beads], as it is possible to display all kinds of different proteins on their surface. To easily create them, we designed a [https://2012.igem.org/Team:LMU-Munich/Bacillus_BioBricks/Sporovector '''Sporo'''vector] in which you just have to insert the gene encoding your fusion protein of choice.</p>

Latest revision as of 17:11, 26 October 2012

iGEM Ludwig-Maximilians-Universität München Beadzillus

Team-LMU Photo2.jpg

The LMU-Munich team is exuberantly happy about the great success at the World Championship Jamboree in Boston. Our project Beadzillus finished 4th and won the prize for the "Best Wiki" (with Slovenia) and "Best New Application Project".

IGEM HQ LMU prize.jpg

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