As biological research becomes easier and easier with the development of new tools and increased understanding, there is also increased danger. Not only are many pathogen sequences freely available on the internet, but the DNA production process has become so simple and well understood, that any amateur biologist or hobbyist now has the ability to synthesize their own sequences. While in some ways this can be positive, the this also poses a clear threat, and exemplifies a need for an increase in pathogen detection tools. Many oligo companies now screen their orders for pathogen sequences, but there are many online resources that have yet to be analyzed, including the BioBrick repository.