Team:Grenoble/Project/Abstract

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Revision as of 13:23, 26 July 2012

Project Description

The Grenoble iGEM team intends to build an ultra sensitive detector. The goal is to produce a detector that can hugely amplify a given signal. It consists of three modules:

  1. the first gets the signal
  2. the second amplifies it
  3. the third sends the output

The detection module is a membrane receptor that once activated by a chemical compound actuates an amplification loop. The loop enhances the cell response efficiency.
The amplification system contains a genetic feed forward loop. It acts as a biologic loud filter aiming at reducing false positive outputs. Once amplified and filtered the signal is transmitted to the neighboring bacteria. In this way a noticeable fluorescent emission is generated.

Scheme of the concept

Scheme of the concept

Theoretical response of the device depending on the input signal

Theoretical response of the device depending on the input signal