Team:Grenoble/Modeling/Notebook/August/33

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<h1>August</h1>
 
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<a href="http://2012.igem.org/Team:Grenoble/Modeling/Notebook/August/31">Week 31</a> •
 
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<a href="http://2012.igem.org/Team:Grenoble/Modeling/Notebook/August/32">Week 32</a> •
 
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<a href="http://2012.igem.org/Team:Grenoble/Modeling/Notebook/August/33">Week 33</a> •
 
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<a href="http://2012.igem.org/Team:Grenoble/Modeling/Notebook/August/34">Week 34</a> •
 
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<a href="http://2012.igem.org/Team:Grenoble/Modeling/Notebook/August/35">Week 35</a>
 
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<h1> Week 33: August 13<span class="exposant">th</span> to 19<span class="exposant">th</span> </h1>
 
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<b> Goal </b>
 
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<li>End of the script for the stochastic and analysis</li>
 
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<li>Beginning of the equilibrium analysis to answer the question : Is the system always turned on ?</li>
 
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<li>Set a new deterministic model for the receptor</li>
 
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<b> Completion </b>
 
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The script is definitely done but the parameters are not fixed. Thus we can't make simulations and analyse the results.
 
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We learnt how to use isoclines.
 
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For the receptor we chose a phenomenological extension of Goldbeter-Koshland biochemical switch model[1]. </br>The system is now much simple. We have 2 equations and 8 parameters.</br></br></br>
 
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[1] Alejandra C.Ventura, Jacques-A. Sepulchre, Sofia D.Merajver. A Hidden Feedback in Signaling Cascades Is Revealed. PLOS Computational Biology, 2008, 4, 3, e1000041.
 
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Latest revision as of 00:13, 25 September 2012