Team:Grenoble/Human Practice/Meeting

From 2012.igem.org

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<h1> Meeting with Dr. Max Maurin</h1>
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<h1> Meeting with MD PhD Max Maurin</h1>
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As we wanted to produce a useful detection device in the medical field, we contacted early on in the project <a href="http://www.antimicrobe.org/authors/max_maurin.asp">MD PhD Max Maurin</a> heading the infectious agents’ department in the institute of Biology and pathology-CHU Grenoble.
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As we wanted to produce a useful detection device in the medical field, we early contacted Pr. Max Maurin head leader of the infectious agents’ department in the institute of Biology and pathology-CHU Grenoble.
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<span class="legend"><center>From left to right: Dr.Max Maurin, Nadia, Jérôme</center></span>
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<center>From left to right: Dr.Max Maurin, Nadia, Jérôme</center>
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<span class="legend"><center>Jérôme explaining the project in order to have the specialist's opinion</center></span>
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<center>Jérôme explaining the project in order to have the specialist's opinion</center>
 
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He explained to us that one of the major problems in the hospital is nosocomial infections by <i>Staphylococcus aureus</i>. Indeed, in France, nosocomial infections due to <i>S. aureus</i> represent 18.9% of the total nosocomial infections, which is the highest rate after <i>E. coli</i> (24.7%) <a href="#ref">[1]</a>.
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The professor explained to us that one of the major problems in the hospital is nosocomial infections by Staphylococcus Aureus. Indeed, in France, nosocomial infections due to Staphylococcus Aureus represent 18,9% of the total nosocomial infections, which is the highest rate after E.Coli (24.7%) [1]
 
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In the case of <i>S. aureus</i> two types of detection are used in the laboratory: either PCR or selective growth on agar plates.
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In the case of Staphylococcus Aureus two types of detection are used in the laboratory: whether PCR or common plate tests.
 
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If the doctors need a quick answer (within a couple of hours) or suspect resistance to Methicillin they use PCR which is quick but still expensive and needs qualified staff. It costs between 15 and 20 €.
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If the doctors need a quick answer (within a couple of hours) or suspect resistance to Methicillin they use PCR which is quick but still expensive and needs qualified staff: It costs between 15 and 20 euros.
 
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Otherwise, they use the common technique of plate tests. This technique is less expensive (2 ) but needs much more time (48 hours).
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Otherwise, they use the common technique of plate tests. This technique is less expensive (2 euros) but needs much more time (48 hours).
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<span class="legend"><center>Dr.Max Maurin explaining the different pathogen detection methods</center></span>
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<center>Dr.Max Maurin explaining the different pathogen detection methods</center>
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The professor also explained that because of the expenses, last year, the hospital couldn’t afford to make an assessment of the contamination level with S.Aureus for all the hospital rooms. Such a study should be done at least once a year in order to ensure a safe environment for the medical staff as well as the patients.
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The professor also explained that because of the expenses, last year, the hospital couldn’t afford to make an assessment of the contamination level with <i>S. aureus</i> for all the hospital rooms. Such a study should be done at least once a year in order to ensure a safe environment for the medical staff as well as the patients.
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So designing a quick, cheap and reliable ''S. Aureus'' detector is a real need. It will not only increase patients life expectancy by helping prescribe the right treatment on time, but it will also help decrease the expenses and ensure a safe and non-contaminated environment.  
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So designing a quick, cheap (see our <a href="https://2012.igem.org/Team:Grenoble/Human_Practice/Cost">cost assessment</a>) and reliable <i>S. aureus</i> detector is a real need. It would not only increase patients life expectancy by helping prescribe the right treatment on time, but it would also help decrease the expenses and ensure a safe and non-contaminated environment inside the hospital.  
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<h1>References</h1>
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<h1 id="ref">References</h1>
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<ul><li>[1]  <a href="http://www.securitesoins.fr/fic_bdd/pdf_fr_fichier/12405659920_LES_INFECTIONS_NOSOCOMIALES.pdf">http://www.securitesoins.fr/fic_bdd/pdf_fr_fichier/12405659920_LES_INFECTIONS_NOSOCOMIALES.pdf</a> </li></ul>
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<b>[1]</b> <a href="http://www.securitesoins.fr/fic_bdd/pdf_fr_fichier/12405659920_LES_INFECTIONS_NOSOCOMIALES.pdf" target="_blank">http://www.securitesoins.fr/fic_bdd/pdf_fr_fichier/12405659920_LES_INFECTIONS_NOSOCOMIALES.pdf</a>
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Latest revision as of 01:03, 26 September 2012

iGEM Grenoble 2012

Project

Meeting with MD PhD Max Maurin


As we wanted to produce a useful detection device in the medical field, we contacted early on in the project MD PhD Max Maurin heading the infectious agents’ department in the institute of Biology and pathology-CHU Grenoble.

From left to right: Dr.Max Maurin, Nadia, Jérôme


Jérôme explaining the project in order to have the specialist's opinion


He explained to us that one of the major problems in the hospital is nosocomial infections by Staphylococcus aureus. Indeed, in France, nosocomial infections due to S. aureus represent 18.9% of the total nosocomial infections, which is the highest rate after E. coli (24.7%) [1].

In the case of S. aureus two types of detection are used in the laboratory: either PCR or selective growth on agar plates.

If the doctors need a quick answer (within a couple of hours) or suspect resistance to Methicillin they use PCR which is quick but still expensive and needs qualified staff. It costs between 15 and 20 €.

Otherwise, they use the common technique of plate tests. This technique is less expensive (2 €) but needs much more time (48 hours).


Dr.Max Maurin explaining the different pathogen detection methods


The professor also explained that because of the expenses, last year, the hospital couldn’t afford to make an assessment of the contamination level with S. aureus for all the hospital rooms. Such a study should be done at least once a year in order to ensure a safe environment for the medical staff as well as the patients.

So designing a quick, cheap (see our cost assessment) and reliable S. aureus detector is a real need. It would not only increase patients life expectancy by helping prescribe the right treatment on time, but it would also help decrease the expenses and ensure a safe and non-contaminated environment inside the hospital.

References

[1] http://www.securitesoins.fr/fic_bdd/pdf_fr_fichier/12405659920_LES_INFECTIONS_NOSOCOMIALES.pdf