Team:Grenoble/Biology/Notebook/June/week 26

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iGEM Grenoble 2012

Project
week 23 week 24 week 25 week 26

Week 26: June 25th to July 01st

For the detection module, we decided to work on a modified membrane receptor. It consists of two merged E. coli membrane receptors. The extracellular part is the extracellular part of Tap, a dipeptide membrane receptor. The cytoplasmic part is the cytoplasmic part of the EnvZ receptor, which has the ability to activate OmpR (by phosphorilation) which is a transcription factor.

receptor



It will be a proof of concept for a bigger system which is a complete pathogene detection module :

receptor_2

1st network : with amplifier 1 (RsmA-rsmY)

amplifier_1