Team:Grenoble/Biology/Notebook/June

From 2012.igem.org

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<h1> Week 23: June 04<span style={font-size: 0.7em;}>th</span> to 10<span style={font-size: 0.7em;}>th</span> </h1>
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<h1> Week 23: June 04<span style="font-size: 0.7em;">th</span> to 10<span style="font-size: 0.7em;">th</span> </h1>
During this week we chose the project on which we wanted to work. <br/>
During this week we chose the project on which we wanted to work. <br/>
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Revision as of 09:01, 6 August 2012

iGEM Grenoble 2012

Project
week 23 week 24 week 25 week 26

Week 23: June 04th to 10th

During this week we chose the project on which we wanted to work.

We decided to create a system which can detect a pathogene, like Staphylococcus aureus, for example.

We intend to build an ultra sensitive detector. The goal is to produce a detector which can hugely amplify a really low input signal. It consists of three modules:
  1. the first gets the signal
  2. the second amplifies it
  3. the third sends the output

The detection module is a membrane receptor that once activated by a biomolecule actuates an amplification loop. The loop enhances the cell response efficiency.
The amplification system contains a genetic feed forward loop. It acts as a biologic loud filter aiming at reducing false positive outputs. Once amplified and filtered the signal is transmitted to the neighboring bacteria. In this way a noticeable fluorescent emission is generated.

Scheme of the concept

Scheme of the concept

Theoretical response of the device depending on the input signal

Theoretical response of the device depending on the input signal