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Team:Grenoble/Biology/Notebook/June
From 2012.igem.org
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| - | <h1> Week 23: June | + | <h1> Week 23: June 04<span style={font-size: 0.7em;}>th</span> to 10<span style={font-size: 0.7em;}>th</span> </h1> |
During this week we chose the project on which we wanted to work. <br/> | During this week we chose the project on which we wanted to work. <br/> | ||
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Revision as of 08:57, 6 August 2012
Week 23: June 04th to 10th
During this week we chose the project on which we wanted to work.We decided to create a system which can detect a pathogene, like Staphylococcus aureus, for example.
We intend to build an ultra sensitive detector. The goal is to produce a detector which can hugely amplify a really low input signal. It consists of three modules:
- the first gets the signal
- the second amplifies it
- the third sends the output
The detection module is a membrane receptor that once activated by a biomolecule actuates an amplification loop. The loop enhances the cell response efficiency.
The amplification system contains a genetic feed forward loop. It acts as a biologic loud filter aiming at reducing false positive outputs. Once amplified and filtered the signal is transmitted to the neighboring bacteria. In this way a noticeable fluorescent emission is generated.
Scheme of the concept
Theoretical response of the device depending on the input signal
