Team:Grenoble/Biology/Notebook/June

From 2012.igem.org

(Difference between revisions)
Line 12: Line 12:
<br/>
<br/>
<h1> Week 23: June 04th to 10th </h1>
<h1> Week 23: June 04th to 10th </h1>
-
During this week we chose the project on which we wanted to work.
+
During this week we chose the project on which we wanted to work. <br/>
-
 
+
<br/>
-
We decided to create a system which can detect a pathogene, like Staphylococcus aureus, for example.
+
We decided to create a system which can detect a pathogene, like Staphylococcus aureus, for example.<br/>
-
 
+
<br/>
-
We intend to build an ultra sensitive detector. The goal is to produce a detector which can hugely amplify a really low input signal. It consists of three modules:
+
We intend to build an ultra sensitive detector. The goal is to produce a detector which can hugely amplify a really low input signal. It consists of three modules:<br/>
-
 
+
<ol>
-
the first gets the signal
+
    <li>the first gets the signal</li>
-
the second amplifies it
+
    <li>the second amplifies it</li>
-
the third sends the output
+
    <li>the third sends the output</li>
 +
</ol>
The detection module is a membrane receptor that once activated by a biomolecule actuates an amplification loop. The loop enhances the cell response efficiency.
The detection module is a membrane receptor that once activated by a biomolecule actuates an amplification loop. The loop enhances the cell response efficiency.

Revision as of 08:40, 6 August 2012

iGEM Grenoble 2012

Project
week 23 week 24 week 25 week 26

Week 23: June 04th to 10th

During this week we chose the project on which we wanted to work.

We decided to create a system which can detect a pathogene, like Staphylococcus aureus, for example.

We intend to build an ultra sensitive detector. The goal is to produce a detector which can hugely amplify a really low input signal. It consists of three modules:
  1. the first gets the signal
  2. the second amplifies it
  3. the third sends the output
The detection module is a membrane receptor that once activated by a biomolecule actuates an amplification loop. The loop enhances the cell response efficiency. The amplification system contains a genetic feed forward loop. It acts as a biologic loud filter aiming at reducing false positive outputs. Once amplified and filtered the signal is transmitted to the neighboring bacteria. In this way a noticeable fluorescent emission is generated.