Team:Freiburg

From 2012.igem.org

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This is a template page. READ THESE INSTRUCTIONS.
 
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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
 
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You <strong>MUST</strong> have all of the pages listed in the menu below with the names specified. PLEASE keep all of your pages within your teams namespace. 
 
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{|align="justify"
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|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
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|[[Image:FreiGEM_logo2.png|left|no frame|Your team picture]]
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|[[Image:Freiburg_logo.png|200px|right|frame]]
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|The iGEM Team Freiburg 2012 (FreiGEM) is dedicated to standardize the synthesis of Transactivator-like (TAL) proteins, i.e. DNA-binding proteins. In contrast to zinc-finger proteins they consist of domain-like repeats in their primary structure that differ only by two amino acids. These two amino acids of a given repeat determine which DNA base the repeat will bind to. By providing efficient mechanisms to combine the different repeats in order to target a certain DNA sequence of around 14bp the FreiGEM team is working towards establishing a standardized kit. This one tube essay will provide the user with an easy, quick and cost-efficient way to design his or her individualized TAL protein in just a glance. However, FreiGEM 2012 will not stop there but move beyond that by also including different TAL effectors in the kit. These are enzymes that can be linked to the DNA-binding domain and thereby act only around a specific region in the genome - perefectly suited for epigenetic application, for instance by using histone modifying enzymes.
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''Tell us more about your project.  Give us background.  Use this as the abstract of your project. Be descriptive but concise (1-2 paragraphs)''
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''Stay tuned to FreiGEM 2012 - we will keep you in the loop.''
|[[Image:Freiburg_team.png|right|frame|Your team picture]]
|[[Image:Freiburg_team.png|right|frame|Your team picture]]
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<!--- The Mission, Experiments --->
<!--- The Mission, Experiments --->
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!align="center"|[[Team:Freiburg|Home]]
!align="center"|[[Team:Freiburg|Home]]
!align="center"|[[Team:Freiburg/Team|Team]]
!align="center"|[[Team:Freiburg/Team|Team]]

Revision as of 09:14, 8 May 2012

Your team picture
The iGEM Team Freiburg 2012 (FreiGEM) is dedicated to standardize the synthesis of Transactivator-like (TAL) proteins, i.e. DNA-binding proteins. In contrast to zinc-finger proteins they consist of domain-like repeats in their primary structure that differ only by two amino acids. These two amino acids of a given repeat determine which DNA base the repeat will bind to. By providing efficient mechanisms to combine the different repeats in order to target a certain DNA sequence of around 14bp the FreiGEM team is working towards establishing a standardized kit. This one tube essay will provide the user with an easy, quick and cost-efficient way to design his or her individualized TAL protein in just a glance. However, FreiGEM 2012 will not stop there but move beyond that by also including different TAL effectors in the kit. These are enzymes that can be linked to the DNA-binding domain and thereby act only around a specific region in the genome - perefectly suited for epigenetic application, for instance by using histone modifying enzymes.

Stay tuned to FreiGEM 2012 - we will keep you in the loop.

File:Freiburg team.png
Your team picture
Team Freiburg


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