Team:Fatih-Medical

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{|align="justify"
 
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|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
 
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|[[Image:Fatih-Medical_logo.png|200px|right|frame]]
 
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''Tell us more about your project.  Give us background.  Use this as the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
 
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|[[Image:Fatih-Medical_team.png|right|frame|Your team picture]]
 
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|align="center"|[[Team:Fatih-Medical | Team Fatih-Medical]]
 
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<!--- The Mission, Experiments --->
<!--- The Mission, Experiments --->
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!align="center"|[[Team:Fatih-Medical/Attributions|Attributions]]
!align="center"|[[Team:Fatih-Medical/Attributions|Attributions]]
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|'''CANCEL the CANCER'''
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'''A SynBio Approach to the Diagnosis of Cancer'''
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''Our project is based on the early diagnosis of cancer. Cancer tissues disseminate cells called CTCs (Circulating Tumor Cells) to the blood during early phases of the disease. On the surface of these cells, there are specific antigens called EpCAM. Furthermore, the oncogenic DNA of a CTC contains specific mutations. Our goal is to place appropiate antibodies for EpCAM antigens and DNA binding TALE proteins into the bacterial cell wall so that we can detect CTCs or the DNA which is released by the lysis of the tumor cells and proceeds to the blood. In this way, we will hopefully diagnose cancer before it paves the way to metastasis. To amplificate the signal, we want to use quorum sensing mechanism in our bacteria. Finally, to prevent the production of possible unwilling GMOs; we plan to induce self-destruction in our bacteria via emitting light. ''
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Revision as of 18:12, 14 July 2012


Home Team Official Team Profile Project Parts Submitted to the Registry Modeling Notebook Safety Attributions


CANCEL the CANCER


A SynBio Approach to the Diagnosis of Cancer

Our project is based on the early diagnosis of cancer. Cancer tissues disseminate cells called CTCs (Circulating Tumor Cells) to the blood during early phases of the disease. On the surface of these cells, there are specific antigens called EpCAM. Furthermore, the oncogenic DNA of a CTC contains specific mutations. Our goal is to place appropiate antibodies for EpCAM antigens and DNA binding TALE proteins into the bacterial cell wall so that we can detect CTCs or the DNA which is released by the lysis of the tumor cells and proceeds to the blood. In this way, we will hopefully diagnose cancer before it paves the way to metastasis. To amplificate the signal, we want to use quorum sensing mechanism in our bacteria. Finally, to prevent the production of possible unwilling GMOs; we plan to induce self-destruction in our bacteria via emitting light.