http://2012.igem.org/wiki/index.php?title=Team:Evry/Safety&feed=atom&action=historyTeam:Evry/Safety - Revision history2024-03-28T17:35:38ZRevision history for this page on the wikiMediaWiki 1.16.0http://2012.igem.org/wiki/index.php?title=Team:Evry/Safety&diff=181916&oldid=prevCaroGallo at 21:45, 25 September 20122012-09-25T21:45:26Z<p></p>
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</table>CaroGallohttp://2012.igem.org/wiki/index.php?title=Team:Evry/Safety&diff=181048&oldid=prevCaroGallo at 20:53, 25 September 20122012-09-25T20:53:25Z<p></p>
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</table>CaroGallohttp://2012.igem.org/wiki/index.php?title=Team:Evry/Safety&diff=181018&oldid=prevCaroGallo at 20:51, 25 September 20122012-09-25T20:51:57Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>Public safety </h4></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>Public safety </h4></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We are using embryos and tadpoles in laboratory conditions, they will never be released to the environment so we will not cause any environmental safety issues. They are going to be euthanized before reaching their reproductive age.</p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We are using embryos and tadpoles in laboratory conditions, they will never be released to the environment so we will not cause any environmental safety issues. They are going to be euthanized before reaching their reproductive age.</p></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h3>2. Do any of the new BioBrick parts (or devices) that you made this year raise any safety issues? </h3></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h3>2. Do any of the new BioBrick parts (or devices) that you made this year raise any safety issues? </h3></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>No, there are no potentially dangerous biobricks in our constructs. All DNA constuctions and <i>E. coli</i> expressing resistance genes are disposed of properly, either by autoclaving or adding bleach.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>No, there are no potentially dangerous biobricks in our constructs. All DNA constuctions and <i>E. coli</i> expressing resistance genes are disposed of properly, either by autoclaving or adding bleach.</div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h3>3. Is there a local biosafety group, committee, or review board at your institution? </h3></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h3>3. Is there a local biosafety group, committee, or review board at your institution? </h3></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>If yes, what does your local biosafety group think about your project?</h4></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>If yes, what does your local biosafety group think about your project?</h4></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Environmental measures has been considered wastes are being disposed of in a specific containers and thereafter treated in accordance to the type of wastes whether biological or chemical.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Environmental measures has been considered wastes are being disposed of in a specific containers and thereafter treated in accordance to the type of wastes whether biological or chemical.</div></td></tr>
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</table>CaroGallohttp://2012.igem.org/wiki/index.php?title=Team:Evry/Safety&diff=180978&oldid=prevCaroGallo at 20:50, 25 September 20122012-09-25T20:50:08Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>did you document these issues in the Registry?</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>did you document these issues in the Registry?</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>how did you manage to handle the safety issue?</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>how did you manage to handle the safety issue?</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>How could other teams learn from your experience?</h4></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>How could other teams learn from your experience?</h4></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>No, there are no potentially dangerous biobricks in our constructs. All DNA constuctions and <i>E. coli</i> expressing resistance genes are disposed of properly, either by autoclaving or adding bleach.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>No, there are no potentially dangerous biobricks in our constructs. All DNA constuctions and <i>E. coli</i> expressing resistance genes are disposed of properly, either by autoclaving or adding bleach.</div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>If yes, what does your local biosafety group think about your project?</h4></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>If yes, what does your local biosafety group think about your project?</h4></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>If no, which specific biosafety rules or guidelines do you have to consider in your country?</h4></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>If no, which specific biosafety rules or guidelines do you have to consider in your country?</h4></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>In our host laboratory- iSSB there is no local committee which deals with the biosafety. However there is health and safety officer Prof. Ioana Popescu, Dr. Dominique Zeliszewski and people who are trained in first aid. Emergency numbers and first-aid rules are easily visible in each room of the institute. ISSB is a part of CNRS (French national center for research) .Consequently, the institute conforms to safety rules and regulations set by CNRS. </br></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>In our host laboratory- iSSB there is no local committee which deals with the biosafety. However there is health and safety officer Prof. Ioana Popescu, Dr. Dominique Zeliszewski and people who are trained in first aid. Emergency numbers and first-aid rules are easily visible in each room of the institute. ISSB is a part of CNRS (French national center for research) .Consequently, the institute conforms to safety rules and regulations set by CNRS. </br></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h3>4. Do you have any other ideas how to deal with safety issues that could be useful for future iGEM competitions? How could parts, devices and systems be made even safer through biosafety engineering? </h3></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h3>4. Do you have any other ideas how to deal with safety issues that could be useful for future iGEM competitions? How could parts, devices and systems be made even safer through biosafety engineering? </h3></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Safety in synthetic biology has always been both researchers’ and public’s concern. As a result, having an IGEM biosafety guidelines set for new IGEMers with what to use versus what is off limits. As for what can be done to make IGEM parts, devices, and systems safer, we propose the following potential solutions:</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Safety in synthetic biology has always been both researchers’ and public’s concern. As a result, having an IGEM biosafety guidelines set for new IGEMers with what to use versus what is off limits. As for what can be done to make IGEM parts, devices, and systems safer, we propose the following potential solutions:</div></td></tr>
</table>CaroGallohttp://2012.igem.org/wiki/index.php?title=Team:Evry/Safety&diff=180853&oldid=prevCaroGallo at 20:44, 25 September 20122012-09-25T20:44:56Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>Researcher safety </h4></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>Researcher safety </h4></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We are working with level 1 safety organisms, which are not dangerous for researchers:</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We are working with level 1 safety organisms, which are not dangerous for researchers:</div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Any part of our project is not potentially dangerous or harmful for public. All DNA constuctions and <i>E. coli</i> expressing resistance genes (e.g. Ampicillin and Kanamycin) are disposed of properly, either by autoclaving or adding bleach. </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Any part of our project is not potentially dangerous or harmful for public. All DNA constuctions and <i>E. coli</i> expressing resistance genes (e.g. Ampicillin and Kanamycin) are disposed of properly, either by autoclaving or adding bleach. </div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>Environmental safety </h4></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>Environmental safety </h4></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p>For our biological waste we are using the special plastic bags which are marked as biohazard, and which are disposed in the specially designated areas. All contaminated waste is treated as <b>'Bio-Hazardous Waste'</b> and is decontaminated (autoclaved) before being put into a red trash bag or a sealed medical waste box. The bio-hazard bag is placed in a pre-chosen area for picking up. Appropriate measures for waste disposal are taken. Waste is not washed down the sink or thrown into public dust-bins.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p>For our biological waste we are using the special plastic bags which are marked as biohazard, and which are disposed in the specially designated areas. All contaminated waste is treated as <b>'Bio-Hazardous Waste'</b> and is decontaminated (autoclaved) before being put into a red trash bag or a sealed medical waste box. The bio-hazard bag is placed in a pre-chosen area for picking up. Appropriate measures for waste disposal are taken. Waste is not washed down the sink or thrown into public dust-bins.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We are using embryos and tadpoles in laboratory conditions, they will never be released to the environment so we will not cause any environmental safety issues. They are going to be euthanized before reaching their reproductive age.</p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We are using embryos and tadpoles in laboratory conditions, they will never be released to the environment so we will not cause any environmental safety issues. They are going to be euthanized before reaching their reproductive age.</p></div></td></tr>
</table>CaroGallohttp://2012.igem.org/wiki/index.php?title=Team:Evry/Safety&diff=180818&oldid=prevCaroGallo at 20:43, 25 September 20122012-09-25T20:43:33Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h2>Safety questions </h2></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h2>Safety questions </h2></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h3>1. Would any of your project ideas raise safety issues in terms of: </h3></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h3>1. Would any of your project ideas raise safety issues in terms of: </h3></div></td></tr>
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</table>CaroGallohttp://2012.igem.org/wiki/index.php?title=Team:Evry/Safety&diff=180734&oldid=prevCaroGallo at 20:39, 25 September 20122012-09-25T20:39:14Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>Environmental safety </h4></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h4>Environmental safety </h4></div></td></tr>
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</table>CaroGallohttp://2012.igem.org/wiki/index.php?title=Team:Evry/Safety&diff=180688&oldid=prevCaroGallo at 20:37, 25 September 20122012-09-25T20:37:10Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <li> <b>Sodium hydroxide: </b> Harmful if swallowed. May cause adverse reproductive effects based upon animal studies. May cause liver and kidney damage. Causes burns by all exposure routes. </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <li> <b>Sodium hydroxide: </b> Harmful if swallowed. May cause adverse reproductive effects based upon animal studies. May cause liver and kidney damage. Causes burns by all exposure routes. </div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <li><b>Target Organs: </b></i>Kidneys, liver, cardiovascular system. Causes eye and skin burns in contact, destructive to the tissue of the mucous membranes and airway, chronic exposition can cause lungs and ovaries cancer (tested on hamster).</li></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <li><b>Target Organs: </b></i>Kidneys, liver, cardiovascular system. Causes eye and skin burns in contact, destructive to the tissue of the mucous membranes and airway, chronic exposition can cause lungs and ovaries cancer (tested on hamster).</li></div></td></tr>
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<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline"><tr><td class="caption"><a href="http://www.who.int/csr/resources/publications/biosafety/en/Biosafety7.pdf">http://www.who.int/csr/resources/publications/biosafety/en/Biosafety7.pdf</a></ins></div></td></tr>
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</table>CaroGallohttp://2012.igem.org/wiki/index.php?title=Team:Evry/Safety&diff=180645&oldid=prevCaroGallo at 20:35, 25 September 20122012-09-25T20:35:05Z<p></p>
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</table>CaroGallohttp://2012.igem.org/wiki/index.php?title=Team:Evry/Safety&diff=180607&oldid=prevCaroGallo at 20:33, 25 September 20122012-09-25T20:33:03Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The laboratory has been classified as to biosafety categories and complies to French law (French Biosafety-National Legislation that deals with biohazards and GMO/GMM). </br></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>The laboratory has been classified as to biosafety categories and complies to French law (French Biosafety-National Legislation that deals with biohazards and GMO/GMM). </br></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Environmental measures has been considered wastes are being disposed of in a specific containers and thereafter treated in accordance to the type of wastes whether biological or chemical.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Environmental measures has been considered wastes are being disposed of in a specific containers and thereafter treated in accordance to the type of wastes whether biological or chemical.</div></td></tr>
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</table>CaroGallo