Team:Amsterdam/project/molecular design

     $('#sub-menu').append("The Cellular Logbook is build on the natural occurring epigenetic phenomenon of methylation. Each sensor is able to expres a zinc finger and methyltransferase fusion protein (ZnF-Mtase). The ZnF-Mtase binds to its Memory Part (MP), which consists of a restriction site that is targeted by the methyltransferase, and two binding sites that are specific to the zinc finger. Upon binding, the methyltransferase will methylate the restriction site. The methylated restriction site is inaccessible to restriction enzymes. By digesting the Memory Part with the restriction enzyme and performing gel electrophoresis, it can be read out if the ZnF-Mtase has come to expression and as such if the related signal has been present.")