Jamboree/Title and Abstract

From 2012.igem.org

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=Antibody Generation System – Maturation, Selection and Production in CHO Cells=
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==Project Abstract and Title==
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<span style="font-weight:bold; font-size:110%; color:red"> Due September 7</span>
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Please provide ONE project title of up to '''15 words''' and ONE project abstract of '''100 to 150 words''' to be included in the Jamboree program.  The program will include all team projects and abstracts and will be a way to communicate what each team's project is about. 
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Antibodies are highly important molecules for research and therapy but their generation is laborious and time consuming. We established a novel streamlined workflow for obtaining antibodies by incorporating all standard steps such as antibody maturation, selection and production in one genetic system implemented into a eukaryotic cell line. We stably transfect an antibody construct into CHO cells and mimic maturation by using the enzyme AID (activation induced deaminase), which is known to induce somatic hypermutation. For selection, we are testing and deploying a versatile and continuous viral system as well as magnetic beads and cell sorting. Finally, a genetic switch will enable the transition from surface expression to production of soluble antibodies. In addition, we pursue phage display with an antibody fragment to study mutation rate and evolution by AID in prokaryotes. Our system supersedes animal immunization and the smooth process will increase the ready availability of antibodies in various formats.
 
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=ABSTRACK=
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====How to submit your project abstract and title====
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<br>
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<span style="font-weight:bold; font-size:110%; color:red">Note:</span> The submission process for project abstracts and titles has changed! Please submit your project abstract and title using the <strong>new</strong> online system.
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* Log into your [https://igem.org/Team_List?year=2012 official team profile]
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* Under the "Title and Abstract" section, click on "Edit" above the gray box
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* Enter your project title and abstract
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* Basic formatting utilizing the &#60;i&#62; and &#60;b&#62; HTML tags can be used
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It is important that you submit your track selection on time, as the system will be closed on <strong>September 7</strong>.
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Questions can be emailed to <strong>hq AT igem DOT org</strong>.
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''Update:'' See all the project titles and abstracts '''[https://2012.igem.org/Jamboree/Team_Abstracts here]'''!

Latest revision as of 17:40, 29 September 2013

Project Abstract and Title

Due September 7

Please provide ONE project title of up to 15 words and ONE project abstract of 100 to 150 words to be included in the Jamboree program. The program will include all team projects and abstracts and will be a way to communicate what each team's project is about.


How to submit your project abstract and title


Note: The submission process for project abstracts and titles has changed! Please submit your project abstract and title using the new online system.

  • Log into your official team profile
  • Under the "Title and Abstract" section, click on "Edit" above the gray box
  • Enter your project title and abstract
  • Basic formatting utilizing the <i> and <b> HTML tags can be used


It is important that you submit your track selection on time, as the system will be closed on September 7.

Questions can be emailed to hq AT igem DOT org.


Update: See all the project titles and abstracts here!