Team:ETH Zurich/Modeling/UVR8

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Another improvement to be included will focus on improving the negative feedback part of the model. Currently this negative feedback from pABA is modelled with a Hill-like inhibition - in future this should be from first principles which will require an effective absorbance cross-section (?!).
Another improvement to be included will focus on improving the negative feedback part of the model. Currently this negative feedback from pABA is modelled with a Hill-like inhibition - in future this should be from first principles which will require an effective absorbance cross-section (?!).
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Revision as of 08:51, 24 September 2012

Contents

UVR8

UVR8 is a plant protein acting in a pathway to regulate COP and act as a UVB photoreceptor. Due to its

Circuit

The following circuit illustrates the general system properties

ODEs

ODEs

Results

Plots

Outlook

As most cellular proteins containing tryptophan and tyrosine absorb in the UVB range, the theoretical calculations for the rate parameters are a first approximation. Taking this general background absorption into account will refine and provide for a more realistic model.

Another improvement to be included will focus on improving the negative feedback part of the model. Currently this negative feedback from pABA is modelled with a Hill-like inhibition - in future this should be from first principles which will require an effective absorbance cross-section (?!).

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