iGEM UT-Tokyo aim to improve Escherichia coli's intrinsic hydrogen synthesis pathway by transgenics and to make E.coli produces hydrogen more efficiently with a view of using it as an energy source.
Sweetaholic Energy Generator:
Hydrogen Production from Sugar-rich Waste by E.coli
E. coli cells have intrinsic metabolic systems related to synthesis of hydrogen from glucose via formic acid. We are trying to improve the latter part of this metabolic system, the formic acid-hydrogen pathway in two ways. One is by overexpressing a transcriptional gene which enhances/ a step in this pathway, and the other is by repressing the inhibitive gene of the hydrogen production. If we are successful, what we have to do for getting energy is to share our sweets and juices with E. coli.
- by overexpressing a transcriptional gene... in detail: Project H2 E.coli
- by repressing the inhibitive gene... in detail:Project2: Inhibition without Knockout